cDNA cloning of human kidney pyruvate carboxylase.
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- CitationCopy to clipboard
MacKay N, Rigat B, Douglas C, Chen HS, Robinson BH
cDNA cloning of human kidney pyruvate carboxylase.
Biochem Biophys Res Commun. 1994 Jul 29;202(2):1009-14.
- PubMed ID
- 8048912 [ View in PubMed]
- Abstract
cDNA clones covering a total of 4017 bp were isolated corresponding to the full length of the message for human pyruvate carboxylase. The coding sequence consisted of a stretch of 3534 bp flanked by a 5' untranslated sequence of 82 bp and a 3' untranslated region of 389 bp excluding the poly-A tail. The translated amino acid sequence of 1178 residues contained consensus sequences for the covalent attachment for biotin, the binding of ATP and the binding of the substrate, pyruvate.