Phototoxic and photoprotective effects of topical isothipendyl.
Article Details
- CitationCopy to clipboard
Moreau A, Dompmartin A, Dubreuil A, Leroy D
Phototoxic and photoprotective effects of topical isothipendyl.
Photodermatol Photoimmunol Photomed. 1995 Apr;11(2):50-4.
- PubMed ID
- 8546983 [ View in PubMed]
- Abstract
Isothipendyl, an H1-receptor antagonist, is an antihistamine used as an antiallergic drug. Its molecular structure is close to the phenothiazines, but it has different photobiological properties. Like phenothiazines, isothipendyl is phototoxic with ultraviolet A (UVA) but it reduces the erythema response to UVB radiation. Isothipenyl seems to have the same protective properties as a sunscreen because its UVB protective properties are effective only if the substance is applied prior to exposure.
DrugBank Data that Cites this Article
- Drugs
- Drug Targets
Drug Target Kind Organism Pharmacological Action Actions Isothipendyl Histamine H1 receptor Protein Humans YesAntagonistDetails