Genome sequence of the radioresistant bacterium Deinococcus radiodurans R1.
Article Details
- CitationCopy to clipboard
White O, Eisen JA, Heidelberg JF, Hickey EK, Peterson JD, Dodson RJ, Haft DH, Gwinn ML, Nelson WC, Richardson DL, Moffat KS, Qin H, Jiang L, Pamphile W, Crosby M, Shen M, Vamathevan JJ, Lam P, McDonald L, Utterback T, Zalewski C, Makarova KS, Aravind L, Daly MJ, Minton KW, Fleischmann RD, Ketchum KA, Nelson KE, Salzberg S, Smith HO, Venter JC, Fraser CM
Genome sequence of the radioresistant bacterium Deinococcus radiodurans R1.
Science. 1999 Nov 19;286(5444):1571-7.
- PubMed ID
- 10567266 [ View in PubMed]
- Abstract
The complete genome sequence of the radiation-resistant bacterium Deinococcus radiodurans R1 is composed of two chromosomes (2,648,638 and 412,348 base pairs), a megaplasmid (177,466 base pairs), and a small plasmid (45,704 base pairs), yielding a total genome of 3,284, 156 base pairs. Multiple components distributed on the chromosomes and megaplasmid that contribute to the ability of D. radiodurans to survive under conditions of starvation, oxidative stress, and high amounts of DNA damage were identified. Deinococcus radiodurans represents an organism in which all systems for DNA repair, DNA damage export, desiccation and starvation recovery, and genetic redundancy are present in one cell.
DrugBank Data that Cites this Article
- Polypeptides
Name UniProt ID Protein RecA P42443 Details S-ribosylhomocysteine lyase Q9RRU8 Details Tryptophan--tRNA ligase 2 Q9RVD6 Details Citrate lyase subunit beta-like protein Q9RUZ0 Details Malto-oligosyltrehalose trehalohydrolase Q9RX51 Details NAD(P)H dehydrogenase (quinone) Q9RYU4 Details Recombination protein RecR Q9ZNA2 Details 50S ribosomal protein L32 P49228 Details