Norgestomet implants maintain pregnancy in ovariectomized heifers.

Article Details

Citation

Kesler DJ

Norgestomet implants maintain pregnancy in ovariectomized heifers.

Theriogenology. 1997 Jul 1;48(1):89-98.

PubMed ID
16728110 [ View in PubMed
]
Abstract

Fifty-five heifers were synchronized with norgestomet and estradiol valerate and artificially inseminated approximately 48 h after the removal of norgestomet implants. Ten days after Al, 15 of the heifers were ovariectomized and then two 15 mg norgestomet/silicone implants were implanted subcutaneously on the convex surface of the ear. The norgestomet/silicone implants were changed every 55 +/-4 d (mean range) thereafter, and the last set of implants was removed 273 d after Al. At 44 d after Al, 65% (26/40) of the control heifers and 53% (8/1 5) of the ovariectomized heifers with norgestomet implants were pregnant (P > 0.10). Two pregnancies were lost in ovariectomized heifers treated with norgestomet (44 to 96 d after Al) and a third pregnancy failed in a heifer that lost 1 of 2 implants 65 to 96 d after Al. Ninety-six days after Al implants were removed from 2 pregnant ovariectomized heifers with norgestomet implants. These 2 heifers were open at 116 d after Al. All 3 ovariectomized heifers with norgestomet implants pregnant at 273 d after Al calved an average of 41 h after the removal of the last set of norgestomet/silicone implants. Dystocia (P < 0.05), retention of fetal membranes (P < 0.01), and calf mortality (P < 0.01) were higher for the ovariectomized heifers with norgestomet implants than for the control heifers.

DrugBank Data that Cites this Article

Drugs