A low energy short hydrogen bond in very high resolution structures of protein receptor--phosphate complexes.

Article Details

Citation

Wang Z, Luecke H, Yao N, Quiocho FA

A low energy short hydrogen bond in very high resolution structures of protein receptor--phosphate complexes.

Nat Struct Biol. 1997 Jul;4(7):519-22.

PubMed ID
9228942 [ View in PubMed
]
Abstract

A very short hydrogen bond between an Asp and a phosphate is established in two high resolution structures (0.98 and 1.05 A). A mutant complex that changes the Asp to an Asn, which forms a normal hydrogen bond, has a similar free energy of binding to the wild type complex, suggesting that the contribution of the short hydrogen bond is not extraordinarily strong.

DrugBank Data that Cites this Article

Polypeptides
NameUniProt ID
Phosphate-binding protein PstSP0AG82Details