Fe(3+) dicitrate transport protein FecA
Details
- Name
- Fe(3+) dicitrate transport protein FecA
- Synonyms
- Iron(III) dicitrate transport protein FecA
- Gene Name
- fecA
- Organism
- Escherichia coli (strain K12)
- Amino acid sequence
>lcl|BSEQ0011335|Fe(3+) dicitrate transport protein FecA MTPLRVFRKTTPLVNTIRLSLLPLAGLSFSAFAAQVNIAPGSLDKALNQYAAHSGFTLSV DASLTRGKQSNGLHGDYDVESGLQQLLDGSGLQVKPLGNNSWTLEPAPAPKEDALTVVGD WLGDARENDVFEHAGARDVIRREDFAKTGATTMREVLNRIPGVSAPENNGTGSHDLAMNF GIRGLNPRLASRSTVLMDGIPVPFAPYGQPQLSLAPVSLGNMDAIDVVRGGGAVRYGPQS VGGVVNFVTRAIPQDFGIEAGVEGQLSPTSSQNNPKETHNLMVGGTADNGFGTALLYSGT RGSDWREHSATRIDDLMLKSKYAPDEVHTFNSLLQYYDGEADMPGGLSRADYDADRWQST RPYDRFWGRRKLASLGYQFQPDSQHKFNIQGFYTQTLRSGYLEQGKRITLSPRNYWVRGI EPRYSQIFMIGPSAHEVGVGYRYLNESTHEMRYYTATSSGQLPSGSSPYDRDTRSGTEAH AWYLDDKIDIGNWTITPGMRFEHIESYQNNAITGTHEEVSYNAPLPALNVLYHLTDSWNL YANTEGSFGTVQYSQIGKAVQSGNVEPEKARTWELGTRYDDGALTAEMGLFLINFNNQYD SNQTNDTVTARGKTRHTGLETQARYDLGTLTPTLDNVSIYASYAYVNAEIREKGDTYGNL VPFSPKHKGTLGVDYKPGNWTFNLNSDFQSSQFADNANTVKESADGSTGRIPGFMLWGAR VAYDFGPQMADLNLAFGVKNIFDQDYFIRSYDDNNKGIYAGQPRTLYMQGSLKF
- Number of residues
- 774
- Molecular Weight
- 85321.005
- Theoretical pI
- 5.75
- GO Classification
- Functionsferric iron transmembrane transporter activity / iron ion binding / receptor activityProcessesferric iron transport / iron ion homeostasis / siderophore transportComponentscell outer membrane / integral component of membrane
- General Function
- Receptor activity
- Specific Function
- FecA is the outer membrane receptor protein in the Fe(3+) dicitrate transport system.
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Cell outer membrane
- Gene sequence
>lcl|BSEQ0011336|Fe(3+) dicitrate transport protein FecA (fecA) ATGACGCCGTTACGCGTTTTTCGTAAAACAACACCTTTGGTTAACACCATTCGCCTGAGC CTGCTGCCGCTGGCCGGTCTCTCGTTTTCCGCTTTTGCTGCACAGGTTAATATCGCACCG GGATCGCTCGATAAAGCGCTCAATCAGTATGCCGCACACAGCGGATTTACCCTCTCGGTT GACGCCAGCCTGACGCGCGGCAAGCAGAGCAACGGCCTGCACGGCGATTACGACGTCGAG AGCGGCCTGCAACAACTGCTGGACGGCAGCGGACTGCAGGTAAAACCGCTGGGAAATAAC AGCTGGACGCTGGAGCCCGCGCCCGCACCAAAAGAAGATGCCCTGACCGTGGTCGGCGAC TGGCTGGGTGATGCGCGTGAAAACGACGTATTTGAACATGCTGGCGCGCGTGACGTGATC CGCCGTGAGGATTTCGCCAAAACCGGCGCAACCACCATGCGTGAGGTACTTAACCGCATC CCTGGCGTCAGCGCGCCGGAAAACAACGGCACCGGCAGCCACGACCTGGCGATGAACTTT GGCATCCGGGGCCTGAACCCGCGCCTCGCCAGCCGCTCGACCGTCCTGATGGACGGCATC CCCGTCCCCTTCGCCCCTTACGGTCAGCCGCAGCTTTCACTGGCTCCCGTTTCGCTCGGC AACATGGATGCCATTGACGTGGTACGCGGTGGTGGTGCGGTGCGTTACGGACCGCAGAGC GTGGGCGGCGTGGTGAACTTTGTTACCCGTGCCATTCCGCAGGACTTTGGTATCGAGGCG GGCGTGGAAGGTCAGCTCAGCCCAACCTCTTCACAAAACAACCCGAAAGAGACGCACAAC CTGATGGTGGGCGGCACAGCGGACAACGGTTTTGGCACCGCGCTGCTCTACTCCGGCACG CGCGGCAGTGACTGGCGCGAGCACAGCGCCACCCGCATCGACGACCTGATGCTGAAAAGC AAATATGCGCCGGATGAGGTGCACACCTTCAACAGCCTGCTGCAATATTACGACGGTGAA GCCGACATGCCCGGTGGCCTGTCTCGCGCGGATTACGACGCCGATCGCTGGCAATCCACC CGCCCGTATGACCGCTTCTGGGGTCGTCGCAAGCTGGCGAGCCTGGGCTACCAGTTCCAG CCAGACAGCCAGCATAAATTCAACATTCAGGGGTTCTACACCCAAACCCTGCGCAGCGGC TACCTGGAGCAAGGCAAACGCATCACCCTCTCGCCGCGTAACTACTGGGTGCGCGGTATT GAGCCACGCTACAGCCAGATCTTTATGATCGGCCCTTCCGCGCACGAAGTGGGCGTGGGC TATCGCTATTTGAATGAATCAACGCATGAAATGCGTTACTACACCGCCACCAGCAGCGGG CAGTTGCCGTCCGGCTCAAGCCCTTACGACCGCGATACGCGTTCCGGCACCGAGGCGCAC GCCTGGTATCTGGATGACAAAATCGACATCGGCAACTGGACCATCACGCCGGGTATGCGT TTCGAACATATCGAGTCATACCAGAACAACGCCATCACAGGCACGCACGAAGAAGTGAGC TATAACGCACCGCTTCCGGCGTTGAACGTGCTCTATCACCTGACTGACAGCTGGAATCTT TATGCAAACACTGAAGGCTCGTTCGGCACCGTACAGTACAGCCAGATTGGCAAGGCTGTG CAAAGCGGCAATGTTGAACCGGAAAAAGCGCGAACCTGGGAACTCGGTACCCGCTACGAC GACGGCGCGCTGACGGCGGAAATGGGGCTGTTCCTGATTAACTTTAACAATCAGTACGAC TCCAACCAGACCAACGACACCGTCACTGCACGTGGCAAAACGCGCCATACCGGGCTGGAA ACGCAGGCACGTTACGATCTGGGTACGCTAACGCCAACGCTTGATAACGTTTCCATCTAC GCCAGCTATGCGTATGTGAACGCGGAAATCCGCGAGAAAGGCGACACCTACGGCAATCTG GTACCATTCTCCCCGAAACATAAAGGCACGCTGGGCGTGGACTACAAGCCAGGAAACTGG ACGTTCAATCTGAACAGCGATTTCCAGTCCAGCCAGTTTGCGGATAACGCCAATACGGTG AAAGAGAGCGCCGACGGCAGTACCGGCCGCATTCCCGGCTTCATGCTCTGGGGCGCACGC GTGGCGTATGACTTTGGCCCGCAGATGGCAGATCTGAACCTGGCATTCGGTGTGAAAAAC ATCTTCGACCAGGACTACTTCATCCGCTCTTATGACGACAACAACAAAGGCATCTATGCA GGCCAGCCGCGCACGCTGTATATGCAGGGGTCGTTGAAGTTCTGA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P13036 UniProtKB Entry Name FECA_ECOLI GenBank Protein ID 145922 GenBank Gene ID M20981 - General References
- Pressler U, Staudenmaier H, Zimmermann L, Braun V: Genetics of the iron dicitrate transport system of Escherichia coli. J Bacteriol. 1988 Jun;170(6):2716-24. [Article]
- Burland V, Plunkett G 3rd, Sofia HJ, Daniels DL, Blattner FR: Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes. Nucleic Acids Res. 1995 Jun 25;23(12):2105-19. [Article]
- Blattner FR, Plunkett G 3rd, Bloch CA, Perna NT, Burland V, Riley M, Collado-Vides J, Glasner JD, Rode CK, Mayhew GF, Gregor J, Davis NW, Kirkpatrick HA, Goeden MA, Rose DJ, Mau B, Shao Y: The complete genome sequence of Escherichia coli K-12. Science. 1997 Sep 5;277(5331):1453-62. [Article]
- Hayashi K, Morooka N, Yamamoto Y, Fujita K, Isono K, Choi S, Ohtsubo E, Baba T, Wanner BL, Mori H, Horiuchi T: Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Mol Syst Biol. 2006;2:2006.0007. Epub 2006 Feb 21. [Article]
- Van Hove B, Staudenmaier H, Braun V: Novel two-component transmembrane transcription control: regulation of iron dicitrate transport in Escherichia coli K-12. J Bacteriol. 1990 Dec;172(12):6749-58. [Article]
- Staudenmaier H, Van Hove B, Yaraghi Z, Braun V: Nucleotide sequences of the fecBCDE genes and locations of the proteins suggest a periplasmic-binding-protein-dependent transport mechanism for iron(III) dicitrate in Escherichia coli. J Bacteriol. 1989 May;171(5):2626-33. [Article]
- Davies BW, Kohanski MA, Simmons LA, Winkler JA, Collins JJ, Walker GC: Hydroxyurea induces hydroxyl radical-mediated cell death in Escherichia coli. Mol Cell. 2009 Dec 11;36(5):845-60. doi: 10.1016/j.molcel.2009.11.024. [Article]