Menstruation-Inducing Agents

Name
Menstruation-Inducing Agents
Accession Number
DBCAT001155
Description

Chemical compounds that induce menstruation either through direct action on the reproductive organs or through indirect action by relieving another condition of which amenorrhea is a secondary result. (From Dorland, 27th ed)

Drugs
DrugDrug Description
MifepristoneA cortisol receptor blocker used to treat Cushing's syndrome, and to terminate pregnancies up to 70 days gestation.
SulprostoneA prostaglandin analogue used to treat post-partum hemorrhaging, induce medical abortion, and induce labour in instances of in utero fetal death.
Drugs & Drug Targets
DrugTargetType
MifepristoneProgesterone receptortarget
MifepristoneGlucocorticoid receptortarget
MifepristoneCytochrome P450 3A4enzyme
MifepristoneCytochrome P450 3A5enzyme
MifepristoneP-glycoprotein 1transporter
MifepristoneMultidrug resistance-associated protein 1transporter
MifepristoneCytochrome P450 2D6enzyme
MifepristoneProstate-specific antigentarget
MifepristoneNuclear receptor subfamily 1 group I member 2target
MifepristoneBile salt export pumptransporter
MifepristoneCytochrome P450 2C8enzyme
MifepristoneCytochrome P450 2C9enzyme
MifepristoneSolute carrier organic anion transporter family member 1B1transporter
MifepristoneSolute carrier organic anion transporter family member 1B3transporter