Chondroitinases and Chondroitin Lyases
- Name
- Chondroitinases and Chondroitin Lyases
- Accession Number
- DBCAT002907
- Description
Enzymes which catalyze the elimination of glucuronate residues from chondroitin A,B, and C or which catalyze the hydrolysis of sulfate groups of the 2-acetamido-2-deoxy-D-galactose 6-sulfate units of chondroitin sulfate. EC 4.2.2.-.
- Drugs
Drug Drug Description Galsulfase A recombinant human enzyme used as replacement enzyme therapy for the treatment of of adults and children with Mucopolysaccharidosis VI, a rare genetic disorder caused by a deficiency of a lysosomal enzyme. Elosulfase alfa A lysosomal glycosaminoglycan (GAG)-specific enzyme indicated as an enzyme replacement therapy for Mucopolysaccharidosis type IV A. - Drugs & Drug Targets
Drug Target Type Galsulfase Perilipin-3 target Galsulfase Dermatan sulfate target