Harringtonines
- Name
- Harringtonines
- Accession Number
- DBCAT005005
- Description
Tetracyclic spiro-BENZAZEPINES isolated from the seeds of CEPHALOTAXUS. They are esters of the alkaloid cephalotaxine and may be effective as antineoplastic agents.
- Drugs
Drug Drug Description Omacetaxine mepesuccinate A cephalotaxine used in the treatment of Chronic Myeloid Leukemia (CML) that is intolerant to or resistant to two or more tyrosine kinase inhibitors. - Drugs & Drug Targets
Drug Target Type Omacetaxine mepesuccinate 50S ribosomal protein L2 target Omacetaxine mepesuccinate 60S ribosomal protein L3 target