Dual Endothelin Type A Receptor/Ang II Subtype 1 Receptor Antagonist (DEARA)

Name

Dual Endothelin Type A Receptor/Ang II Subtype 1 Receptor Antagonist (DEARA)

Accession Number

DBCAT005808

Description

Not Available

Drugs

Drug	Drug Description
Sparsentan	An endothelin and angiotensin II receptor antagonist indicated to reduce proteinuria in adults with primary immunoglobulin A nephropathy at risk of rapid disease progression.

Drugs & Drug Targets

Drug	Target	Type
Sparsentan	Endothelin-1 receptor	target
Sparsentan	Type-2 angiotensin II receptor	target
Sparsentan	Cytochrome P450 3A4	enzyme
Sparsentan	Cytochrome P450 2B6	enzyme
Sparsentan	Cytochrome P450 2C9	enzyme
Sparsentan	Cytochrome P450 2C19	enzyme
Sparsentan	P-glycoprotein 1	transporter
Sparsentan	ATP-binding cassette sub-family G member 2	transporter
Sparsentan	Solute carrier organic anion transporter family member 1B3	transporter
Sparsentan	Solute carrier family 22 member 8	transporter
Sparsentan	Type-1 angiotensin II receptor	target