Polyether Toxins

Name

Polyether Toxins

Accession Number

DBCAT005897

Description

Polycyclic polyether polyketides most often produced by marine organisms, e.g., DINOFLAGELLATES. Many polyether marine toxins are ionophores and neurotoxins and responsible for seafood poisoning.

Drugs

Drug	Drug Description
Bryostatin 1	Bryostatin 1 has been investigated for the treatment of HIV Infection and Alzheimer's Disease.

Drugs & Drug Targets

Drug	Target	Type
Bryostatin 1	Cytochrome P450 3A4	enzyme
Bryostatin 1	Protein kinase C alpha type	target
Bryostatin 1	Protein kinase C epsilon type	target
Bryostatin 1	Caspase-8	target
Bryostatin 1	Protein unc-13 homolog B	target
Bryostatin 1	Serine/threonine-protein kinase D1	target
Bryostatin 1	T-lymphocyte activation antigen CD86	target
Bryostatin 1	Prostaglandin G/H synthase 2	target
Bryostatin 1	G1/S-specific cyclin-D1	target
Bryostatin 1	Tumor necrosis factor	target