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Hint Older versions of DrugBank files are available here.

Hint The DrugCard format is being deprecated. It does not include any of the new information in DrugBank 3, it is available for backwards compatibility only. In future, please use the XML version of DrugBank.

DrugBank is offered to the public as a freely available resource. Use and re-distribution of the data, in whole or in part, for commercial purposes requires explicit permission of the authors and explicit acknowledgment of the source material (DrugBank) and the original publication (see below). We ask that users who download significant portions of the database cite the DrugBank paper in any resulting publications.

  1. DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-41.
    PMID: 21059682
  2. DrugBank: a knowledgebase for drugs, drug actions and drug targets. Wishart DS, Knox C, Guo AC, Cheng D, Shrivastava S, Tzur D, Gautam B, Hassanali M. Nucleic Acids Res. 2008 Jan;36(Database issue):D901-6.
    PMID: 18048412
  3. DrugBank: a comprehensive resource for in silico drug discovery and exploration. Wishart DS, Knox C, Guo AC, Shrivastava S, Hassanali M, Stothard P, Chang Z, Woolsey J. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D668-72.
    PMID: 16381955

Full Database

Description Format Download
All Drugs, including target, transporter, carrier, and enzyme information XML Download | Schema
All Drugs, including target and enzyme information DrugCard Download

Drug External Links and Identifiers

Description Format Download
Links to external databases and external identifiers for approved drugs CSV (Microsoft Excel compatible) Download

Protein Identifiers (CSV, Microsoft Excel compatible)

Hint Protein identifiers include external IDs to resources such as UniProt and PDB. These downloads are divided first by protein/compound type (target, transporter, etc.). Secondly they are divided by drug group (approved, illicit, etc.). Lastly, they are divided by whether the target/enzyme/transporter/carrier was marked as directly related to the mechanism of action for at least one of the associated drugs (this is the called the known pharmacological action).
Note that each row in the export CSV file also includes a concatenated list of DrugBank drugs IDs (semi-colon delimited) as the last column.

Drug Target Identifiers

Description Download all Download all with known pharmacological action
All Drugs Download all Download all with known pharmacological action
Approved Drugs Download all Download all with known pharmacological action
Small molecule Drugs Download all Download all with known pharmacological action
Experimental Drugs Download all Download all with known pharmacological action
Nutraceutical Drugs Download all Download all with known pharmacological action
Illicit Drugs Download all Download all with known pharmacological action
Withdrawn Drugs Download all Download all with known pharmacological action

Drug Enzyme Identifiers

Description Download all Download all with known pharmacological action
All Drugs Download all Download all with known pharmacological action
Approved Drugs Download all Download all with known pharmacological action
Small molecule Drugs Download all Download all with known pharmacological action
Experimental Drugs Download all Download all with known pharmacological action
Nutraceutical Drugs Download all Download all with known pharmacological action
Illicit Drugs Download all Download all with known pharmacological action
Withdrawn Drugs Download all Download all with known pharmacological action

Drug Transporter Identifiers

Description Download all Download all with known pharmacological action
All Drugs Download all Download all with known pharmacological action
Approved Drugs Download all Download all with known pharmacological action
Small molecule Drugs Download all Download all with known pharmacological action
Experimental Drugs Download all Download all with known pharmacological action
Nutraceutical Drugs Download all Download all with known pharmacological action
Illicit Drugs Download all Download all with known pharmacological action
Withdrawn Drugs Download all Download all with known pharmacological action

Drug Carrier Identifiers

Description Download all Download all with known pharmacological action
All Drugs Download all Download all with known pharmacological action
Approved Drugs Download all Download all with known pharmacological action
Small molecule Drugs Download all Download all with known pharmacological action
Experimental Drugs Download all Download all with known pharmacological action
Nutraceutical Drugs Download all Download all with known pharmacological action
Illicit Drugs Download all Download all with known pharmacological action
Withdrawn Drugs Download all Download all with known pharmacological action

Structures (in SDF Format):

Data Set SDF File
All Drugs Download
Approved Drugs Download
Small molecule Drugs Download
Experimental Drugs Download
Nutraceutical Drugs Download
Illicit Drugs Download
Withdrawn Drugs Download

Protein/Gene Sequences (in FASTA Format):

Drug Target Sequences

Data Set Protein Sequences Gene Sequences
All Drug Targets Download Download
Approved Drug Targets Download Download
Small molecule Drug Targets Download Download
Experimental Drug Targets Download Download
Nutraceutical Drug Targets Download Download
Illicit Drug Targets Download Download
Withdrawn Drug Targets Download Download

Drug Enzyme Sequences

Data Set Protein Sequences Gene Sequences
All Drug Enzymes Download Download
Approved Drug Enzymes Download Download
Small molecule Drug Enzymes Download Download
Experimental Drug Enzymes Download Download
Nutraceutical Drug Enzymes Download Download
Illicit Drug Enzymes Download Download
Withdrawn Drug Enzymes Download Download

Drug Transporter Sequences

Data Set Protein Sequences Gene Sequences
All Drug Transporters Download Download
Approved Drug Transporters Download Download
Small molecule Drug Transporters Download Download
Experimental Drug Transporters Download Download
Nutraceutical Drug Transporters Download Download
Illicit Drug Transporters Download Download
Withdrawn Drug Transporters Download Download

Drug Carrier Sequences

Data Set Protein Sequences Gene Sequences
All Drug Carriers Download Download
Approved Drug Carriers Download Download
Small molecule Drug Carriers Download Download
Experimental Drug Carriers Download Download
Nutraceutical Drug Carriers Download Download
Illicit Drug Carriers Download Download
Withdrawn Drug Carriers Download Download

Biotech Drug Sequences

Data Set Protein Sequences
Biotech Drugs Download