Crovalimab
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Crovalimab
- DrugBank Accession Number
- DB16128
- Background
Crovalimab is under investigation in clinical trial NCT03157635 (Study to Assess Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Crovalimab in Healthy Volunteers and Participants With Paroxysmal Nocturnal Hemoglobinuria).
- Type
- Biotech
- Groups
- Investigational
- Synonyms
- Complement c5 inhibitory humanized recycling monoclonal antibody (rg-6107 )
- Crovalimab
- Immunoglobulin g1, anti-(human complement c5)(humanized ro7112689 heavy chain), disulfide with humanized ro7112689 light chain, dimer
- External IDs
- RG-6107
- RG6107
- RO-7112689
- RO7112689
- SKY-59
- SKY59
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- H9KH1GP3UU
- CAS number
- 1917321-26-6
References
- General References
- Not Available
- External Links
- Not Available
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 3 Active Not Recruiting Treatment Paroxysmal Nocturnal Haemoglobinuria (PNH) 2 3 Recruiting Treatment Atypical Hemolytic Uremic Syndrome(aHUS) 2 3 Recruiting Treatment Paroxysmal Nocturnal Haemoglobinuria (PNH) 1 3 Withdrawn Treatment Guillain-Barré Syndrome (GBS) 1 2 Recruiting Treatment Sickle Cell Disease (SCD) 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
Drug created at December 15, 2020 18:13 / Updated at February 21, 2021 18:55