Dociparstat sodium
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Identification
- Generic Name
- Dociparstat sodium
- DrugBank Accession Number
- DB16481
- Background
Not Available
- Type
- Small Molecule
- Groups
- Investigational
- Synonyms
- 2,3-o-Desulfated heparin (12000 da)
- Dociparstat sodium
- External IDs
- GM-1892
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
Dociparstat sodium is derived from heparin which, like heparin, alters the activities of the CXCL12/CXCR4 axis and inhibits the interactions of proteins including P-selectin, high mobility group box 1, Platelet Factor 4, and human leukocyte elastase.
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 4O75889WF4
- CAS number
- 177021-00-0
- InChI Key
- Not Available
- InChI
- Not Available
- IUPAC Name
- Not Available
- SMILES
- Not Available
References
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 3 Terminated Treatment Acute Myeloid Leukemia 1 2 Completed Treatment Acute Myeloid Leukemia 1 2 Terminated Treatment Pancreatic Metastatic Cancer 1 2, 3 Terminated Treatment Coronavirus Disease 2019 (COVID‑19) / Lung Injury, Acute (ALI) / Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) 1 1 Completed Treatment Acute Myeloid Leukemia 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
- Not Available
- Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at January 21, 2021 01:47 / Updated at January 18, 2023 15:38