MBS-2320
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- MBS-2320
- DrugBank Accession Number
- DB18059
- Background
Not Available
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 404.91
Monoisotopic: 404.0961414 - Chemical Formula
- C20H21ClN2O3S
- Synonyms
- (1,1'-BIPHENYL)-4-SULFONAMIDE, 4'-CHLORO-2'-CYANO-N-(TRANS-4-HYDROXY-4-METHYLCYCLOHEXYL)-
- 1-METHYL-TRANS-4-(((4'-CHLORO-2'-CYANO-1,1'-BIPHENYL-4-YL)SULFONYL)AMINO)CYCLOHEXANOL
- 4'-chloro-2'-cyano-N-(trans-4-hydroxy-4-methylcyclohexyl)-biphenyl-4-sulfonamide
- External IDs
- HMC-C-01-A
- MBS 2320
- MBS-2320
- MBS2320
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 38E2HYD3AW
- CAS number
- 1642602-54-7
- InChI Key
- PHOYDFRXZMNHIF-IRJFHVNHSA-N
- InChI
- InChI=1S/C20H21ClN2O3S/c1-20(24)10-8-17(9-11-20)23-27(25,26)18-5-2-14(3-6-18)19-7-4-16(21)12-15(19)13-22/h2-7,12,17,23-24H,8-11H2,1H3/t17-,20+
- IUPAC Name
- 4'-chloro-2'-cyano-N-[(1r,4r)-4-hydroxy-4-methylcyclohexyl]-[1,1'-biphenyl]-4-sulfonamide
- SMILES
- C[C@]1(O)CC[C@@H](CC1)NS(=O)(=O)C1=CC=C(C=C1)C1=CC=C(Cl)C=C1C#N
References
- General References
- Not Available
- External Links
- Not Available
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 2 Completed Treatment Rheumatoid Arthritis 2 1 Completed Treatment Rheumatoid Arthritis 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source logP 3.6 Chemaxon pKa (Strongest Acidic) 10.11 Chemaxon pKa (Strongest Basic) -2.8 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 90.19 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 106.1 m3·mol-1 Chemaxon Polarizability 42.83 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at September 08, 2023 20:28 / Updated at September 12, 2023 18:33