NAV

GDP-L-fucose

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
GDP-L-fucose
DrugBank Accession Number
DB18689
Background

Not Available

Type
Small Molecule
Groups
Investigational
Structure
3D
Similar Structures
Weight
Average: 589.344
Monoisotopic: 589.082239121
Chemical Formula
C16H25N5O15P2
Synonyms
  • Gdp-.beta.-l-fucose
  • Gdp-fucose
  • Guanosine 5'-(trihydrogen pyrophosphate), mono(6-deoxy-l-galactopyranosyl) ester
  • Guanosine 5'-diphospho-.beta.-l-fucose
  • Guanosine 5'-pyrophosphate, .beta.-l-fucopyranosyl ester
  • Guanosine pyrophosphate, l-fucosyl ester
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Pharmacology

Indication

Not Available

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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
SM108QK2IH
CAS number
15839-70-0
InChI Key
LQEBEXMHBLQMDB-JGQUBWHWSA-N
InChI
InChI=1S/C16H25N5O15P2/c1-4-7(22)9(24)11(26)15(33-4)35-38(30,31)36-37(28,29)32-2-5-8(23)10(25)14(34-5)21-3-18-6-12(21)19-16(17)20-13(6)27/h3-5,7-11,14-15,22-26H,2H2,1H3,(H,28,29)(H,30,31)(H3,17,19,20,27)/t4-,5+,7-,8-,9+,10+,11-,14+,15+/m0/s1
IUPAC Name
[({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]({[(2R,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy})phosphinic acid
SMILES
C[C@@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=C(N)NC3=O)[C@@H](O)[C@H](O)[C@@H]1O

References

General References
Not Available
KEGG Compound
C00325
ChemSpider
9094247
ChEBI
13332
ChEMBL
CHEMBL1229250
ZINC
ZINC000008551145
PDBe Ligand
GFB
PDB Entries
3zy5 / 3zy6 / 4ap6 / 4bl5 / 5in5 / 5ky3 / 5uxh / 7xpu / 8dti

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
logP-4.2Chemaxon
pKa (Strongest Acidic)1.87Chemaxon
pKa (Strongest Basic)-3.6Chemaxon
Physiological Charge-2Chemaxon
Hydrogen Acceptor Count15Chemaxon
Hydrogen Donor Count9Chemaxon
Polar Surface Area307.2 Å2Chemaxon
Rotatable Bond Count8Chemaxon
Refractivity116.97 m3·mol-1Chemaxon
Polarizability50.05 Å3Chemaxon
Number of Rings4Chemaxon
Bioavailability0Chemaxon
Rule of FiveNoChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleYesChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at October 18, 2023 16:19 / Updated at October 19, 2023 10:36