This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- AVL-3288
- DrugBank Accession Number
- DB18707
- Background
Not Available
- Type
- Small Molecule
- Groups
- Investigational
- Structure
Structure for AVL-3288 (DB18707)
- Weight
- Average: 388.25
Monoisotopic: 387.0541321 - Chemical Formula
- C19H15Cl2N3O2
- Synonyms
- (z)-3-(4-chloroanilino)-n-(4-chlorophenyl)-2-(3-methylisoxazol-5-yl)prop-2-enamide
- Anvylic-3288
- AVL-3288
- External IDs
- AVL-3288
- CCMI
- UCI-4083
- XY-4083
Pharmacology
- Indication
Not Available
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Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- VA80VAX4WF
- CAS number
- 917837-54-8
- InChI Key
- VMAKIACTLSBBIY-BOPFTXTBSA-N
- InChI
- InChI=1S/C19H15Cl2N3O2/c1-12-10-18(26-24-12)17(11-22-15-6-2-13(20)3-7-15)19(25)23-16-8-4-14(21)5-9-16/h2-11,22H,1H3,(H,23,25)/b17-11-
- IUPAC Name
- (2Z)-N-(4-chlorophenyl)-3-[(4-chlorophenyl)amino]-2-(3-methyl-1,2-oxazol-5-yl)prop-2-enamide
- SMILES
- CC1=NOC(=C1)C(=C\NC1=CC=C(Cl)C=C1)\C(=O)NC1=CC=C(Cl)C=C1
References
- General References
- Not Available
- External Links
- ChemSpider
- 13136236
- ChEMBL
- CHEMBL429317
- ZINC
- ZINC000029046739
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 1 Completed Treatment Schizoaffective Disorders / Schizophrenia 1 1 Withdrawn Basic Science Alteration of Cognitive Function 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source logP 4.1 Chemaxon pKa (Strongest Acidic) 13.34 Chemaxon pKa (Strongest Basic) 0.57 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 67.16 Å2 Chemaxon Rotatable Bond Count 5 Chemaxon Refractivity 105.51 m3·mol-1 Chemaxon Polarizability 38.81 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at December 08, 2023 18:49 / Updated at December 09, 2023 17:37