Butriptyline hydrochlorideProduct ingredient for Butriptyline
- Name
- Butriptyline hydrochloride
- Drug Entry
- Butriptyline
Butriptyline is a tricyclic antidepressant which has been used in Europe since 1974. It is the isobutyl side chain homologue of amitriptyline.
- Accession Number
- DBSALT001091
- Structure
Structure for Butriptyline hydrochloride (DBSALT001091)
- Synonyms
- Butriptyline HCl
- UNII
- LIJ2H8658W
- CAS Number
- 5585-73-9
- Weight
- Average: 329.91
Monoisotopic: 329.1910276 - Chemical Formula
- C21H28ClN
- InChI Key
- MCWAFEJHLHEFOD-UHFFFAOYSA-N
- InChI
- InChI=1S/C21H27N.ClH/c1-16(15-22(2)3)14-21-19-10-6-4-8-17(19)12-13-18-9-5-7-11-20(18)21;/h4-11,16,21H,12-15H2,1-3H3;1H
- IUPAC Name
- dimethyl(2-methyl-3-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-2-yl}propyl)amine hydrochloride
- SMILES
- Cl.CC(CC1C2=CC=CC=C2CCC2=C1C=CC=C2)CN(C)C
- External Links
- ChemSpider
- 20461
- ChEMBL
- CHEMBL2106170
- Predicted Properties
Property Value Source Water Solubility 0.000351 mg/mL ALOGPS logP 5.22 ALOGPS logP 5.44 Chemaxon logS -5.9 ALOGPS pKa (Strongest Basic) 10.01 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 1 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 3.24 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 95.95 m3·mol-1 Chemaxon Polarizability 35.63 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five No Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon