Cell division protein FtsZ
Details
- Name
- Cell division protein FtsZ
- Synonyms
- Not Available
- Gene Name
- ftsZ
- Organism
- Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
- Amino acid sequence
>lcl|BSEQ0011297|Cell division protein FtsZ MGFDLDVEKKKENRNIPQANNLKIKVIGVGGAGNNAINRMIEIGIHGVEFVAVNTDLQVL EASNADVKIQIGENITRGLGAGGRPEIGEQAALESEEKIREVLQDTHMVFITAGFGGGTG TGASPVIAKIAKEMGILTVAIVTTPFYFEGPERLKKAIEGLKKLRKHVDTLIKISNNKLM EELPRDVKIKDAFLKADETLHQGVKGISELITKRGYINLDFADIESVMKDAGAAILGIGV GKGEHRAREAAKKAMESKLIEHPVENASSIVFNITAPSNIRMEEVHEAAMIIRQNSSEDA DVKFGLIFDDEVPDDEIRVIFIATRFPDEDKILFPEGDIPAIYRYGLEGLL
- Number of residues
- 351
- Molecular Weight
- 38306.67
- Theoretical pI
- 5.02
- GO Classification
- FunctionsGTP binding / GTPase activityProcessesbarrier septum assembly / FtsZ-dependent cytokinesis / protein polymerizationComponentscell division site / cytoplasm
- General Function
- Gtpase activity
- Specific Function
- Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasm
- Gene sequence
>lcl|BSEQ0011298|Cell division protein FtsZ (ftsZ) ATGGGATTTGACCTTGATGTTGAGAAGAAAAAGGAAAATAGAAACATCCCTCAGGCGAAC AATTTGAAGATAAAAGTCATAGGTGTAGGCGGTGCCGGAAACAATGCCATAAACAGAATG ATAGAAATAGGAATACACGGTGTTGAATTTGTCGCGGTGAACACCGATCTTCAGGTACTG GAGGCTTCTAACGCTGACGTGAAGATTCAGATCGGTGAGAACATCACACGAGGCCTTGGT GCAGGGGGACGTCCCGAGATAGGAGAACAAGCTGCTCTTGAGAGCGAGGAAAAAATCAGA GAAGTGCTCCAGGATACCCACATGGTCTTCATAACTGCAGGGTTCGGAGGAGGGACGGGA ACAGGTGCTTCCCCTGTCATAGCAAAGATAGCCAAAGAAATGGGAATCCTGACTGTAGCC ATAGTGACGACTCCCTTCTATTTCGAAGGCCCGGAGAGACTCAAAAAAGCGATAGAGGGG CTCAAAAAACTTCGAAAACATGTGGATACCCTCATAAAGATATCCAACAACAAACTCATG GAAGAACTCCCGAGGGATGTCAAGATAAAGGATGCTTTTCTGAAGGCTGACGAGACTCTT CACCAGGGAGTGAAAGGAATTTCGGAACTGATAACGAAGAGGGGTTACATAAATCTCGAC TTTGCAGACATAGAGTCGGTAATGAAGGACGCCGGTGCTGCGATCCTTGGCATAGGTGTT GGAAAGGGAGAACACAGAGCGAGAGAAGCTGCTAAGAAGGCTATGGAAAGCAAGTTGATA GAGCATCCTGTAGAAAATGCGAGTTCGATTGTGTTCAATATAACTGCTCCCAGCAATATA AGAATGGAGGAAGTGCACGAAGCAGCTATGATCATAAGGCAGAACAGCAGTGAGGACGCG GACGTCAAATTCGGTCTCATCTTCGATGATGAAGTACCCGATGACGAAATACGTGTGATC TTCATAGCTACAAGATTCCCAGATGAAGACAAGATTCTATTCCCGGAAGGTGACATACCG GCCATTTACAGATACGGTCTGGAGGGGCTTCTTTAA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID O08398 UniProtKB Entry Name FTSZ_THEMA GenBank Protein ID 2104497 GenBank Gene ID U65944 - General References
- Lu C, Stricker J, Erickson HP: FtsZ from Escherichia coli, Azotobacter vinelandii, and Thermotoga maritima--quantitation, GTP hydrolysis, and assembly. Cell Motil Cytoskeleton. 1998;40(1):71-86. [Article]
- Nelson KE, Clayton RA, Gill SR, Gwinn ML, Dodson RJ, Haft DH, Hickey EK, Peterson JD, Nelson WC, Ketchum KA, McDonald L, Utterback TR, Malek JA, Linher KD, Garrett MM, Stewart AM, Cotton MD, Pratt MS, Phillips CA, Richardson D, Heidelberg J, Sutton GG, Fleischmann RD, Eisen JA, White O, Salzberg SL, Smith HO, Venter JC, Fraser CM: Evidence for lateral gene transfer between Archaea and bacteria from genome sequence of Thermotoga maritima. Nature. 1999 May 27;399(6734):323-9. [Article]
- Oliva MA, Cordell SC, Lowe J: Structural insights into FtsZ protofilament formation. Nat Struct Mol Biol. 2004 Dec;11(12):1243-50. Epub 2004 Nov 21. [Article]
- Szwedziak P, Wang Q, Freund SM, Lowe J: FtsA forms actin-like protofilaments. EMBO J. 2012 May 16;31(10):2249-60. doi: 10.1038/emboj.2012.76. Epub 2012 Mar 30. [Article]