Guanylate cyclase soluble subunit beta-2
Details
- Name
- Guanylate cyclase soluble subunit beta-2
- Synonyms
- 4.6.1.2
- GCS-beta-2
- Gene Name
- GUCY1B2
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0052580|Guanylate cyclase soluble subunit beta-2 MSGYDRMLRTLGGNLMEFIENLDALHSYLALSYQEMNAPSFRVERGADGKMFLHYYSDRS GLCHIVPGIIEAVAKDFFDIDVIMDILDMNEEVERTGKKEHVVFLIVQKAHRKMRKTKPK RLQDSQGMERDQEALQAAFLKMKEKYLNVSACPVKKSHWDVVRSIVMFGKGHLMNTFEPI YPERLWIEEKTFCNAFPFHIVFDESLQVKQARVNIQKYVPGLQTQNIQLDEYFSIIHPQV TFNIFSIRRFINSQFVLKTRREMMPVAWQSRTTLKLQGQMIWMESMWCMVYLCSPKLRSL QELEELNMHLSDIAPNDTTRDLILLNQQRLAEIELSNQLERKKEELQVLSKHLAIEKKKT ETLLYAMLPKHVANQLREGKKVAAGEFKSCTILFSDVVTFTNICTACEPIQIVNVLNSMY SKFDRLTSVHAVYKVETIGDAYMVVGGVPVPIGNHAQRVANFALGMRISAKEVTNPVTGE PIQLRVGIHTGPVLADVVGDKMPRYCLFGDTVNTASRMESHGLPNKVHLSPTAYRALKNQ GFKIIERGEIEVKGKGRMTTYFLIQNLNATEDEIMGRSKTPVDHKGSTQKASLPTTKLQG SVQPSCPEHSSLASWLL
- Number of residues
- 617
- Molecular Weight
- 70367.22
- Theoretical pI
- Not Available
- GO Classification
- FunctionsGTP binding / guanylate cyclase activity / heme binding / metal ion bindingProcessescGMP-mediated signalingComponentscytoplasm
- General Function
- Not Available
- Specific Function
- Gtp binding
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasm
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID O75343 UniProtKB Entry Name GCYB2_HUMAN HGNC ID HGNC:4686 - General References
- Behrends S, Vehse K: The beta(2) subunit of soluble guanylyl cyclase contains a human-specific frameshift and is expressed in gastric carcinoma. Biochem Biophys Res Commun. 2000 Apr 29;271(1):64-9. doi: 10.1006/bbrc.2000.2596. [Article]
- Behrends S, Kazmierczak B, Steenpa A, Knauf B, Bullerdiek J, Scholz H, Eiberg H: Assignment of GUCY1B2, the gene coding for the beta2 subunit of human guanylyl cyclase to chromosomal band 13q14.3 between markers D13S168 and D13S155. Genomics. 1999 Jan 1;55(1):126-7. doi: 10.1006/geno.1998.5613. [Article]