Platelet-activating factor acetylhydrolase IB subunit gamma
Details
- Name
- Platelet-activating factor acetylhydrolase IB subunit gamma
- Synonyms
- 3.1.1.47
- PAF acetylhydrolase 29 kDa subunit
- PAF-AH 29 kDa subunit
- PAF-AH subunit gamma
- PAFAH subunit gamma
- PAFAHG
- Gene Name
- PAFAH1B3
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0012858|Platelet-activating factor acetylhydrolase IB subunit gamma MSGEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRE LFSPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKAI VQLVNERQPQARVVVLGLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFVH SDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGAPLLEPAP
- Number of residues
- 231
- Molecular Weight
- 25734.13
- Theoretical pI
- 6.84
- GO Classification
- Functions1-alkyl-2-acetylglycerophosphocholine esterase activity / identical protein binding / platelet-activating factor acetyltransferase activityProcessesbrain development / lipid catabolic process / lipid metabolic process / nervous system development / spermatogenesisComponentscytoplasm / cytosol / extracellular exosome / membrane
- General Function
- Platelet-activating factor acetyltransferase activity
- Specific Function
- Inactivates paf by removing the acetyl group at the sn-2 position. This is a catalytic subunit. Plays an important role during the development of brain.
- Pfam Domain Function
- Lipase_GDSL_2 (PF13472)
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasm
- Gene sequence
>lcl|BSEQ0012859|Platelet-activating factor acetylhydrolase IB subunit gamma (PAFAH1B3) ATGAGTGGAGAGGAGAACCCAGCCAGCAAGCCCACGCCGGTGCAGGACGTACAGGGCGAC GGGCGCTGGATGTCCCTGCACCATCGGTTCGTGGCTGACAGCAAAGATAAGGAACCCGAA GTCGTCTTCATCGGGGACTCCTTGGTCCAGCTCATGCACCAGTGCGAGATCTGGCGCGAG CTCTTCTCTCCTCTGCATGCACTTAACTTTGGCATTGGTGGTGACGGCACACAGCATGTA CTGTGGCGGCTGGAGAATGGGGAGCTGGAACACATCCGGCCCAAGATTGTGGTGGTCTGG GTGGGCACCAACAACCACGGACACACAGCAGAGCAGGTGACTGGTGGCATCAAGGCCATT GTGCAACTGGTGAATGAGCGACAGCCCCAGGCCCGGGTTGTGGTGCTGGGCCTGCTTCCG CGAGGCCAACATCCCAACCCACTTCGGGAGAAGAACCGACAGGTGAACGAGCTGGTACGG GCGGCACTGGCTGGCCACCCTCGGGCCCACTTCCTAGATGCCGACCCTGGCTTTGTGCAC TCAGATGGCACCATCAGCCATCATGACATGTATGATTACCTGCATCTGAGCCGCCTGGGC TACACACCTGTTTGCCGGGCTCTGCACTCCCTGCTTCTGCGTCTGCTGGCCCAAGACCAG GGCCAAGGTGCTCCCCTGCTGGAGCCCGCACCCTAA
- Chromosome Location
- 19
- Locus
- 19q13.1
- External Identifiers
Resource Link UniProtKB ID Q15102 UniProtKB Entry Name PA1B3_HUMAN GenBank Protein ID 1122219 GenBank Gene ID D63391 HGNC ID HGNC:8576 - General References
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