Reaction: Hydroxyphenytoin to 1 product
- Reaction
- Reaction type
- oxidation
- Direction
- Major circulating metabolite?
- No
- Spontaneous?
- No
- Activity
- unknown
- References
- Whirl-Carrillo M, McDonagh EM, Hebert JM, Gong L, Sangkuhl K, Thorn CF, Altman RB, Klein TE: Pharmacogenomics knowledge for personalized medicine. Clin Pharmacol Ther. 2012 Oct;92(4):414-7. doi: 10.1038/clpt.2012.96. [Article]
- Comments
- Not Available
- Enzymes
Enzyme Km Vmax Role Cytochrome P450 2C19 Not Available Not Available confirmed Cytochrome P450 3A5 Not Available Not Available confirmed Cytochrome P450 2C9 Not Available Not Available confirmed Cytochrome P450 3A4 Not Available Not Available implied Cytochrome P450 3A7 Not Available Not Available confirmed Cytochrome P450 2B6 Not Available Not Available confirmed Cytochrome P450 2D6 Not Available Not Available confirmed