Reaction: Lisofylline to 1 product

Reaction
Lisofylline
DB12406
lisofylline 4,5-diol
DBMET01696
Reaction type
Aliphatic hydroxylation
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Shin HS, Slattery JT: CYP3A4-mediated oxidation of lisofylline to lisofylline 4,5-diol in human liver microsomes. J Pharm Sci. 1998 Mar;87(3):390-3. [Article]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 3A4Not AvailableNot Availableimplied
Cytochrome P450 2A6Not AvailableNot Availableimplied