Reaction: N-desmethyl enzalutamide to 1 product

Reaction
N-desmethyl enzalutamide
DBMET03550
Carboxyl metabolite enzalutamide (M1)
DBMET03551
Reaction type
Not Available
Direction
Not Available
Major circulating metabolite?
Yes
Spontaneous?
No
Activity
unknown
References
Not Available
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Liver carboxylesterase 1Not AvailableNot Availableconfirmed
Cytochrome P450 3A4Not AvailableNot Availableimplied
Cytochrome P450 2C8Not AvailableNot Availableimplied