Reaction: Ertapenem to 1 product
- Reaction
- Reaction type
- hydrolysis
- Direction
- Major circulating metabolite?
- Yes
- Spontaneous?
- No
- Activity
- inactive
- References
- Majumdar AK, Musson DG, Birk KL, Kitchen CJ, Holland S, McCrea J, Mistry G, Hesney M, Xi L, Li SX, Haesen R, Blum RA, Lins RL, Greenberg H, Waldman S, Deutsch P, Rogers JD: Pharmacokinetics of ertapenem in healthy young volunteers. Antimicrob Agents Chemother. 2002 Nov;46(11):3506-11. doi: 10.1128/AAC.46.11.3506-3511.2002. [Article]
- Curran M, Simpson D, Perry C: Ertapenem: a review of its use in the management of bacterial infections. Drugs. 2003;63(17):1855-78. doi: 10.2165/00003495-200363170-00006. [Article]
- EMA Approved Drug Products: Ertapenem SUN (ertapenem) Intravenous Infusion [Link]
- Comments
- Not Available
- Enzymes
Enzyme Km Vmax Role Dipeptidase 1 Not Available Not Available confirmed