Reaction: Ertapenem to 1 product

Reaction
Reaction type
hydrolysis
Direction
Major circulating metabolite?
Yes
Spontaneous?
No
Activity
inactive
References
  1. Majumdar AK, Musson DG, Birk KL, Kitchen CJ, Holland S, McCrea J, Mistry G, Hesney M, Xi L, Li SX, Haesen R, Blum RA, Lins RL, Greenberg H, Waldman S, Deutsch P, Rogers JD: Pharmacokinetics of ertapenem in healthy young volunteers. Antimicrob Agents Chemother. 2002 Nov;46(11):3506-11. doi: 10.1128/AAC.46.11.3506-3511.2002. [Article]
  2. Curran M, Simpson D, Perry C: Ertapenem: a review of its use in the management of bacterial infections. Drugs. 2003;63(17):1855-78. doi: 10.2165/00003495-200363170-00006. [Article]
  3. EMA Approved Drug Products: Ertapenem SUN (ertapenem) Intravenous Infusion [Link]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Dipeptidase 1Not AvailableNot Availableconfirmed