Mepenzolate bromideProduct ingredient for Mepenzolate
- Name
- Mepenzolate bromide
- Drug Entry
- Mepenzolate
Mepenzolate is a post-ganglionic parasympathetic inhibitor. It decreases gastric acid and pepsin secretion and suppresses spontaneous contractions of the colon. Mepenzolate diminishes gastric acid and pepsin secretion. Mepenzolate also suppresses spontaneous contractions of the colon. Pharmacologically, it is a post-ganglionic parasympathetic inhibitor. It has not been shown to be effective in contributing to the healing of peptic ulcer, decreasing the rate of recurrence, or preventing complications.
- Accession Number
- DBSALT000451
- Structure
Structure for Mepenzolate bromide (DBSALT000451)
- Synonyms
- Not Available
- UNII
- APX8D32IX1
- CAS Number
- 76-90-4
- Weight
- Average: 420.34
Monoisotopic: 419.10960635 - Chemical Formula
- C21H26BrNO3
- InChI Key
- JRRNZNSGDSFFIR-UHFFFAOYSA-M
- InChI
- InChI=1S/C21H26NO3.BrH/c1-22(2)15-9-14-19(16-22)25-20(23)21(24,17-10-5-3-6-11-17)18-12-7-4-8-13-18;/h3-8,10-13,19,24H,9,14-16H2,1-2H3;1H/q+1;/p-1
- IUPAC Name
- 3-[(2-hydroxy-2,2-diphenylacetyl)oxy]-1,1-dimethylpiperidin-1-ium bromide
- SMILES
- [Br-].C[N+]1(C)CCCC(C1)OC(=O)C(O)(C1=CC=CC=C1)C1=CC=CC=C1
- External Links
- PubChem Compound
- 6461
- ChemSpider
- 6218
- ChEBI
- 6753
- ChEMBL
- CHEMBL1724
- Wikipedia
- Mepenzolate
- Predicted Properties
Property Value Source Water Solubility 0.000565 mg/mL ALOGPS logP -0.75 ALOGPS logP -0.97 Chemaxon logS -5.9 ALOGPS pKa (Strongest Acidic) 11.05 Chemaxon pKa (Strongest Basic) -4.5 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 46.53 Å2 Chemaxon Rotatable Bond Count 5 Chemaxon Refractivity 109.4 m3·mol-1 Chemaxon Polarizability 37.8 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon