Fluorescein sodiumProduct ingredient for Fluorescein
- Name
- Fluorescein sodium
- Drug Entry
- Fluorescein
A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal injuries and corneal trauma. It has been approved by FDA for use in externally applied drugs and cosmetics. (From Merck Index, 12th ed; American Medical Association Drug Evaluations; 1995, p2275)
- Accession Number
- DBSALT001432 (DBSALT000660)
- Structure
- Synonyms
- D & C Yellow no. 8 / D&C Yellow No. 8 / Fluorescein disodium / Fluorescein disodium salt
- UNII
- 93X55PE38X
- CAS Number
- 518-47-8
- Weight
- Average: 376.275
Monoisotopic: 376.03236198 - Chemical Formula
- C20H10Na2O5
- InChI Key
- NJDNXYGOVLYJHP-UHFFFAOYSA-L
- InChI
- InChI=1S/C20H12O5.2Na/c21-11-5-7-15-17(9-11)25-18-10-12(22)6-8-16(18)19(15)13-3-1-2-4-14(13)20(23)24;;/h1-10,21H,(H,23,24);;/q;2*+1/p-2
- IUPAC Name
- disodium 2-(6-oxido-3-oxo-3H-xanthen-9-yl)benzoate
- SMILES
- [Na+].[Na+].[O-]C(=O)C1=CC=CC=C1C1=C2C=CC(=O)C=C2OC2=CC([O-])=CC=C12
- External Links
- ChemSpider
- 10163
- ChEMBL
- CHEMBL1628233
- Wikipedia
- Fluorescein
- Predicted Properties
Property Value Source Water Solubility 0.00962 mg/mL ALOGPS logP 3.49 ALOGPS logP 2.65 Chemaxon logS -4.6 ALOGPS pKa (Strongest Acidic) 3.7 Chemaxon pKa (Strongest Basic) 2.85 Chemaxon Physiological Charge -2 Chemaxon Hydrogen Acceptor Count 5 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 89.49 Å2 Chemaxon Rotatable Bond Count 1 Chemaxon Refractivity 124.8 m3·mol-1 Chemaxon Polarizability 32.36 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon