Chlorcyclizine hydrochlorideProduct ingredient for Chlorcyclizine
- Name
- Chlorcyclizine hydrochloride
- Drug Entry
- Chlorcyclizine
Chlorcyclizine is a first generation phenylpiperazine class antihistamine used to treat urticaria, rhinitis, pruritus, and other allergy symptoms. Chlorcyclizine also has some local anesthetic, anticholinergic, and antiserotonergic properties, and can be used as an antiemetic.
- Accession Number
- DBSALT001022
- Structure
Structure for Chlorcyclizine hydrochloride (DBSALT001022)
- Synonyms
- Chlorcyclizine HCl
- UNII
- NPB7A7874U
- CAS Number
- 14362-31-3
- Weight
- Average: 337.29
Monoisotopic: 336.1160041 - Chemical Formula
- C18H22Cl2N2
- InChI Key
- MSIJLVMSKDXAQN-UHFFFAOYSA-N
- InChI
- InChI=1S/C18H21ClN2.ClH/c1-20-11-13-21(14-12-20)18(15-5-3-2-4-6-15)16-7-9-17(19)10-8-16;/h2-10,18H,11-14H2,1H3;1H
- IUPAC Name
- 1-[(4-chlorophenyl)(phenyl)methyl]-4-methylpiperazine hydrochloride
- SMILES
- Cl.CN1CCN(CC1)C(C1=CC=CC=C1)C1=CC=C(Cl)C=C1
- External Links
- ChemSpider
- 56198
- ChEMBL
- CHEMBL1889091
- Wikipedia
- Chlorcyclizine
- Predicted Properties
Property Value Source Water Solubility 0.0424 mg/mL ALOGPS logP 4.16 ALOGPS logP 4.15 Chemaxon logS -3.8 ALOGPS pKa (Strongest Basic) 7.96 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 6.48 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 89.74 m3·mol-1 Chemaxon Polarizability 33.94 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon