Thonzylamine hydrochlorideProduct ingredient for Thonzylamine
- Name
- Thonzylamine hydrochloride
- Drug Entry
- Thonzylamine
Thonzylamine is an antihistamine and anticholinergic drug. It is available as combination products with Clofedanol or Phenylephrine for temporary relief of symptoms of common cold, hay fever (allergic rhinitis) or other upper respiratory allergies.
- Accession Number
- DBSALT001562
- Structure
- Synonyms
- Thonzylamine HCl
- UNII
- 6K9YKD48Y4
- CAS Number
- 63-56-9
- Weight
- Average: 322.84
Monoisotopic: 322.1560391 - Chemical Formula
- C16H23ClN4O
- InChI Key
- HRYJPHOTGFERGT-UHFFFAOYSA-N
- InChI
- InChI=1S/C16H22N4O.ClH/c1-19(2)11-12-20(16-17-9-4-10-18-16)13-14-5-7-15(21-3)8-6-14;/h4-10H,11-13H2,1-3H3;1H
- IUPAC Name
- N-[2-(dimethylamino)ethyl]-N-[(4-methoxyphenyl)methyl]pyrimidin-2-amine hydrochloride
- SMILES
- Cl.COC1=CC=C(CN(CCN(C)C)C2=NC=CC=N2)C=C1
- External Links
- ChemSpider
- 5906
- ChEBI
- 32219
- ChEMBL
- CHEMBL1529802
- Predicted Properties
Property Value Source Water Solubility 0.733 mg/mL ALOGPS logP 2.4 ALOGPS logP 2.42 Chemaxon logS -2.6 ALOGPS pKa (Strongest Basic) 8.62 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 5 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 41.49 Å2 Chemaxon Rotatable Bond Count 7 Chemaxon Refractivity 86.19 m3·mol-1 Chemaxon Polarizability 32.42 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon