Oxolamine phosphateProduct ingredient for Oxolamine
- Name
- Oxolamine phosphate
- Drug Entry
- Oxolamine
Oxolamine is not approved in the USA, it may be marketed elsewhere internationally as a cough suppressant 1. It is listed as a prescription drug in New Zealand legislation 2. Oxolamine is also approved in Taiwan for the treatment of respiratory tract inflamation 3.
- Accession Number
- DBSALT003004
- Structure
Structure for Oxolamine phosphate (DBSALT003004)
- Synonyms
- 1,2,4-Oxadiazole-5-ethanamine, N,N-diethyl-3-phenyl-, phosphate (1:1) / Oxolamine monophosphate / Oxolamine phosphate
- UNII
- DMG78UE3PU
- CAS Number
- 131378-45-5
- Weight
- Average: 343.32
Monoisotopic: 343.129707818 - Chemical Formula
- C14H22N3O5P
- InChI Key
- PSCWWFOVTFSDGZ-UHFFFAOYSA-N
- InChI
- InChI=1S/C14H19N3O.H3O4P/c1-3-17(4-2)11-10-13-15-14(16-18-13)12-8-6-5-7-9-12;1-5(2,3)4/h5-9H,3-4,10-11H2,1-2H3;(H3,1,2,3,4)
- IUPAC Name
- diethyl[2-(3-phenyl-1,2,4-oxadiazol-5-yl)ethyl]amine; phosphoric acid
- SMILES
- OP(O)(O)=O.CCN(CC)CCC1=NC(=NO1)C1=CC=CC=C1
- External Links
- ChemSpider
- 15236
- Predicted Properties
Property Value Source Water Solubility 0.277 mg/mL ALOGPS logP 2.7 ALOGPS logP 3.14 Chemaxon logS -3 ALOGPS pKa (Strongest Basic) 8.96 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 42.16 Å2 Chemaxon Rotatable Bond Count 6 Chemaxon Refractivity 84.15 m3·mol-1 Chemaxon Polarizability 28.62 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon