Troriluzole hydrochlorideProduct ingredient for Troriluzole
- Name
- Troriluzole hydrochloride
- Drug Entry
- Troriluzole
Troriluzole is under investigation in clinical trial NCT03701399 (Troriluzole in Adult Subjects With Spinocerebellar Ataxia).
- Accession Number
- DBSALT003366
- Structure
Structure for Troriluzole hydrochloride (DBSALT003366)
- Synonyms
- BHV-4157 hydrochloride / GLYCINAMIDE, GLYCYLGLYCYL-N2-METHYL-N-(6-(TRIFLUOROMETHOXY)-2-BENZOTHIAZOLYL)-, HYDROCHLORIDE (1:1) / Glycylglycyl-N2-methyl-N-[6-(trifluoromethoxy)-1,3-benzothiazol-2-yl]glycinamide monohydrochloride
- UNII
- BQ5F77DZS3
- CAS Number
- 1926204-76-3
- Weight
- Average: 455.84
Monoisotopic: 455.0641874 - Chemical Formula
- C15H17ClF3N5O4S
- InChI Key
- ZRZLEMQBDKNTLJ-UHFFFAOYSA-N
- InChI
- InChI=1S/C15H16F3N5O4S.ClH/c1-23(13(26)6-20-11(24)5-19)7-12(25)22-14-21-9-3-2-8(4-10(9)28-14)27-15(16,17)18;/h2-4H,5-7,19H2,1H3,(H,20,24)(H,21,22,25);1H
- IUPAC Name
- 2-amino-N-{[methyl({[6-(trifluoromethoxy)-1,3-benzothiazol-2-yl]carbamoyl}methyl)carbamoyl]methyl}acetamide hydrochloride
- SMILES
- Cl.CN(CC(=O)NC1=NC2=CC=C(OC(F)(F)F)C=C2S1)C(=O)CNC(=O)CN
- External Links
- ChemSpider
- 68006993
- ChEMBL
- CHEMBL4297673
- Predicted Properties
Property Value Source logP -0.042 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 3 Chemaxon Polar Surface Area 126.65 Å2 Chemaxon Rotatable Bond Count 8 Chemaxon Refractivity 88.4 m3·mol-1 Chemaxon Polarizability 37.48 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon