Displaying drugs 251 - 257 of 257 in total
Umifenovir
Umifenovir is an indole-based, hydrophobic, dual-acting direct antiviral/host-targeting agent used for the treatment and prophylaxis of influenza and other respiratory infections. It has been in use in Russia for approximately 25 years and in China since 2006. Its invention is credited to a collaboration between Russian scientists from several research...
Investigational
Matched Description: … ,[A191409], hepatitis B and C viruses, chikungunya virus, reovirus, Hantaan virus, and coxsackie virus ... prophylaxis of influenza and other respiratory infections. ... ,[A191391] foot-and-mouth disease,[A191394] Lassa virus,[A191403] Ebola virus,[A191403] herpes simplex …
BG-777
BG-777 is an immunomodulator with proven efficacy against viral and bacterial infections in preclinical studies.
Investigational
Matched Description: … BG-777 is an immunomodulator with proven efficacy against viral and bacterial infections in preclinical …
Dehydroascorbic acid
Dehydroascorbic acid is made from the oxidation of ascorbic acid. This reaction is reversible, but dehydroascorbic acid can instead undergo irreversible hydrolysis to 2,3-diketogulonic acid. Dehydroascorbic acid as well as ascorbic acid are both termed Vitamin C, but the latter is the main form found in humans. In the body,...
Experimental
Matched Description: … In the body, both dehydroascorbic acid and ascorbic acid have similar biological activity as antivirals …
Matched Categories: … Diet, Food, and Nutrition ... Vitamin C and analogues …
Matched Categories: … Diet, Food, and Nutrition ... Vitamin C and analogues …
BTA9881
BTA9881 is a respiratory syncytial virus (RSV) antiviral drug developed by the Australian company Biota Holdings. It is currently in phase I trials.
Investigational
Matched Description: … BTA9881 is a respiratory syncytial virus (RSV) antiviral drug developed by the Australian company Biota …
N4-Hydroxycytidine
N4-Hydroxyctidine, or EIDD-1931, is a ribonucleoside analog which induces mutations in RNA virions.[A193008,A193011] N4-hydroxycytidine was first described in the literature in 1980 as a potent mutagen of bacteria and phage. It has shown antiviral activity against Venezuelan equine encephalitis virus, and the human coronavirus HCoV-NL63 in vitro. N4-hydroxycytodine has been...
Experimental
Matched Description: … [A193026] A [remdesivir] resistant mutant mouse hepatitis virus has also been shown to have increased ... [A193023] It has shown antiviral activity against Venezuelan equine encephalitis virus,[A193008] and ... of bacteria and phage. …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Molnupiravir
Molnupiravir (EIDD-2801, MK-4482) is the isopropylester prodrug of N4-hydroxycytidine.[A193014,A193026] With improved oral bioavailability in non-human primates, it is hydrolyzed in vivo, and distributes into tissues where it becomes the active 5’-triphosphate form. The active drug incorporates into the genome of RNA viruses, leading to an accumulation of mutations known as...
Investigational
Matched Description: … [A193014] A [remdesivir] resistant mutant mouse hepatitis virus has also been shown to have increased ... including SARS-CoV-2, in mice and human airway epithelial cells. ... A193014,A193026] With improved oral bioavailability in non-human primates, it is hydrolyzed _in vivo_, and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Vilobelimab
Vilobelimab is a chimeric monoclonal immunoglobulin G4 (IgG4) antibody that binds to the soluble form of human C5a with high affinity. It consists of mouse anti-human complement factor 5a (C5a) monoclonal binding sites (variable regions of heavy and light chain regions) and human gamma 4 heavy chain and light kappa...
Investigational
Matched Description: … Vilobelimab is a chimeric monoclonal immunoglobulin G4 (IgG4) antibody that binds to the soluble form ... light chain regions) and human gamma 4 heavy chain and light kappa chain constant regions. ... of mouse anti-human complement factor 5a (C5a) monoclonal binding sites (variable regions of heavy and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 251 - 257 of 257 in total