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Displaying drugs 351 - 375 of 419 in total
6-Aminohexyl-uridine-C1,5'-diphosphate
Experimental
Matched Iupac: … 1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphinic acid …
AVE-2865
Experimental
Matched Iupac: … [2-({[(2-chloro-4,5-difluorophenyl)formamido]carbonyl}amino)-4-fluorophenyl]piperidine-4-carboxylic acid …
IQP-0528
IQP-0528 is under investigation in clinical trial NCT03082690 (ImQuest (IQP) DuoGel Phase 1 Pharmacokinetic Study).
Investigational
Telcagepant
Telcagepant has been investigated for the treatment of Migraine. It is an antagonist of the receptor for calcitonin gene-related peptide (CGRP), a primary neuropeptide involved in the pathophysiology of migraine. CGRP and its receptors are found in areas of the central and peripheral nervous system that are important for the...
Investigational
Matched Description: … CGRP and its receptors are found in areas of the central and peripheral nervous system that are important ... During migraine attacks, CGRP activates these receptors and facilitates the transmission of pain impulses …
2'deoxy-Thymidine-5'-Diphospho-Alpha-D-Glucose
Experimental
Matched Iupac: … 5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy})phosphinic acid …
Eribaxaban
Experimental
Landiolol
Landiolol is a rapid-acting beta-blocker used for rapid ventricular rate control.
Investigational
OXIMINOARYLSULFONAMIDE
Experimental
AZD-7762
AZD7762 has been investigated for the treatment of Cancer, Solid Tumors, and Advanced Solid Malignancies.
Investigational
Matched Description: … AZD7762 has been investigated for the treatment of Cancer, Solid Tumors, and Advanced Solid Malignancies …
FR236913
Experimental
BMS-986142
BMS-986142 is under investigation in clinical trial NCT02880670 (Pharmacokinetics and Metabolism Study of Radiolabeled BMS-986142 in Healthy Male Subjects).
Investigational
Matched Description: … BMS-986142 is under investigation in clinical trial NCT02880670 (Pharmacokinetics and Metabolism Study …
Talinolol
Talinolol has been investigated for the basic science of Gastrointestinal Motility Disorder.
Investigational
KP-1461
KP-1461 is a potent, non-chain-terminating, mutagenic deoxyribonucleoside analogue. Designated a DNA covert nucleoside, the drug consists of a modified base that incorporates randomly into HIV and pairs with multiple bases.
Investigational
Matched Description: … Designated a DNA covert nucleoside, the drug consists of a modified base that incorporates randomly into HIV and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Rebastinib
Rebastinib has been used in trials studying the treatment of Chronic Myeloid Leukemia. It is an inhibitor of Tie2 tyrosine kinase receptor and an antineoplastic agent.
Investigational
Matched Description: … It is an inhibitor of Tie2 tyrosine kinase receptor and an antineoplastic agent. …
Uridine-5'-diphosphate-mannose
Experimental
Matched Iupac: … hydroxy({[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy})phosphoryl]oxy})phosphinic acid …
CP-547632
CP-547632 has been used in trials studying the treatment of Ovarian Cancer, Lung Neoplasms, Ovarian Neoplasms, Peritoneal Neoplasms, and Fallopian Tube Cancer, among others.
Investigational
Matched Description: … studying the treatment of Ovarian Cancer, Lung Neoplasms, Ovarian Neoplasms, Peritoneal Neoplasms, and …
Merimepodib
Merimepodib (VX-497) is a novel noncompetitive inhibitor of IMPDH. Merimepodib is orally bioavailable and inhibits the proliferation of primary human, mouse, rat, and dog lymphocytes at concentrations of approximately 100 nM.
Investigational
Matched Description: … Merimepodib is orally bioavailable and inhibits the proliferation of primary human, mouse, rat, and dog …
Displaying drugs 351 - 375 of 419 in total