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Displaying drugs 26 - 50 of 50 in total

Lipegfilgrastim

Lipegfilgrastim, previously known as XM22, is a pegylated, recombinant granulocyte colony-stimulating factor (G-CSF) that was synthetized using a highly site-specific glycoPEGylation technology . It is used as an alternate to DB00019 for prophylactic use in cancer patients receiving chemotherapy and at risk for developing chemotherapy-induced neutropenia. Since July 2013, lipegfilgrastim...
Approved
Investigational
Matched Description: … Lipegfilgrastim is a covalent conjugate of [DB00099] with a single methoxy polyethylene glycol (PEG) ... Neutropenia and febrile neutropenia (FN) are frequent and potentially fatal complications that occur ... life-threatening infection and sepsis. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …

Sodium sulfate

Sodium Sulfate Anhydrous is the anhydrous, sodium salt form of sulfuric acid. Sodium sulfate anhydrous disassociates in water to provide sodium ions and sulfate ions. Sodium ion is the principal cation of the extracellular fluid and plays a large part in the therapy of fluid and electrolyte disturbances. Sodium sulfate...
Approved
Vet approved
Matched Description: … fluid and electrolyte disturbances. ... does not disturb normal electrolyte balance and does not lead to absorption or excretion of water and ... Sodium sulfate anhydrous disassociates in water to provide sodium ions and sulfate ions. …
Matched Mixtures name: … Polyethylene Glycol 3350 and Electrolytes ... Polyethylene Glycol-3350 and Electrolytes ... Polyethylene Glycol-3350 and Electrolytes with Flavor Pack …
Matched Categories: … Alimentary Tract and Metabolism …

Chloric acid

Approved
Experimental
Matched Mixtures name: … Polyethylene Glycol 3350 and electrolytes - Unflavored …

Antihemophilic factor (recombinant), PEGylated

Antihemophilic Factor (Recombinant), PEGylated, was approved by the FDA in December 2016 as the product Adynovate [FDA label]. Antihemophilic Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor VIII (2,332 amino acids with a molecular weight (MW) of approximately 280 kDa) covalently conjugated with at least one molecule of...
Approved
Investigational
Matched Description: … PEGylation is the covalent attachment of a polyethylene glycol polymer, called PEG, to a drug or protein ... glycol (MW 20 kDa) [FDA label]. ... PEGylation decreases factor VIII clearance and allowing for an increased duration of drug circulation …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 3000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 250 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 1000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

Peginesatide

Peginesatide is a synthetic peptide attached to polyethylene glycol for the treatment of anemia. The polyethylene glycol moiety helps make the drug less immunogenic and prolongs its plasma half-life. Chemically, peginesatide is designed to mimic the pharmacological activity of erythropoietin, but is not a replica of the structure itself. Peginesatide...
Approved
Investigational
Matched Description: … The polyethylene glycol moiety helps make the drug less immunogenic and prolongs its plasma half-life ... Peginesatide is a synthetic peptide attached to polyethylene glycol for the treatment of anemia. ... of two 21-amino acid chains that are covalently bonded by a linker derived from iminodiacetic acid and …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …

Sodium chloride

Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular organisms. It is listed...
Approved
Vet approved
Matched Description: … or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and ... Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular …
Matched Mixtures name: … Polyethylene Glycol 3350 and Electrolytes ... Polyethylene Glycol-3350 and Electrolytes ... Polyethylene Glycol-3350 and Electrolytes with Flavor Pack …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Products: … Walgreens Infants and Childrens Saline Nasal …

Polyethylene glycol 3500

Experimental
Matched Synonyms: … Polyethylene glycol 3500 …
Matched Name: … Polyethylene glycol 3500 …
Matched Products: … Polyethylene Glycol (3350) …

Heptaethylene glycol

Experimental
Matched Synonyms: … Heptaethylene glycol, Peg330 …
Matched Name: … Heptaethylene glycol …

Triethylene glycol

Experimental
Matched Name: … Triethylene glycol …

1-Deoxy-1-Thio-Heptaethylene Glycol

Experimental
Matched Name: … 1-Deoxy-1-Thio-Heptaethylene Glycol …

PEG-uricase

PEG-uricase, a polyethylene glycol ("PEG") conjugate of recombinant porcine uricase (urate oxidase), which breaks down the uric acid deposits is being studied in Phase III clinical trials for the treatment of severe, treatment-refractory gout in the United States in 2006.
Investigational
Matched Synonyms: … Polyethylene glycol-modified uricase …
Matched Description: … PEG-uricase, a polyethylene glycol ("PEG") conjugate of recombinant porcine uricase (urate oxidase), …
Matched Categories: … Enzymes and Coenzymes …

PEG-interleukin-2

Investigational
Matched Synonyms: … Polyethylene glycol-modified recombinant interleukin-2 …

fb-PMT

Investigational
Matched Synonyms: … glycol ... glycol ... '-Bis({4-[3,5-diiodo-4-(1-methylene-1,2,3-triazol-4-ylmethoxy)phenoxy]-3,5-diiodophenyl}acetic acid)polyethylene …

Pegcrisantaspase

Pegcrisantaspase is under investigation in clinical trial NCT02257684 (A Dose Confirmation and Pharmacokinetic Study of Pegcrisantaspase Administered as Intravenous (IV) Infusion in Children and Young Adults With Acute Lymphoblastic Leukemia (ALL) /Lymphoblastic Lymphoma (LBL). Following Hypersensitivity to Pegaspargase (Oncaspar)).
Investigational
Matched Synonyms: … POLYETHYLENE-GLYCOL-ERWINIA-CHRISANTHEMI-L-ASPARAGINASE …
Matched Description: … Study of Pegcrisantaspase Administered as Intravenous (IV) Infusion in Children and Young Adults With ... Pegcrisantaspase is under investigation in clinical trial NCT02257684 (A Dose Confirmation and Pharmacokinetic …

Quercetin

Quercetin is a flavonol widely distributed in plants. It is an antioxidant, like many other phenolic heterocyclic compounds. Glycosylated forms include RUTIN and quercetrin.
Experimental
Investigational
Matched Synonyms: … poly (lactide-co-glycolide)-polyethylene glycol nanoparticles encapsulating quercetin …
Matched Description: … Glycosylated forms include RUTIN and quercetrin. …

3,6,9,12,15-PENTAOXAHEPTADECAN-1-OL

Experimental

2-(2-{2-[2-(2-{2-[2-(2-Ethoxy-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethanol, Polyethyleneglycol Peg400

Experimental

2-(2-{2-[2-(2-Methoxy-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethanol

Experimental

(Hydroxyethyloxy)Tri(Ethyloxy)Octane

Experimental

2-{2-[2-2-(Methoxy-Ethoxy)-Ethoxy]-Ethoxy}-Ethanol

Experimental

3,6,9,12,15-PENTAOXATRICOSAN-1-OL

Experimental

Potassium bitartrate

Potassium bitartate, also referred to as potassium acid tartrate or cream of tartar, is the potassium acid salt of l-( + )-tartaric acid. It is obtained as a byproduct of wine manufacture during the fermentation process. Approved by the FDA as a direct food substance, potassium bitartrate is used as...
Experimental
Matched Description: … Potassium bitartrate has a long history of medical use as a laxative administered as a rectal suppository and …

Poloxamer 407

Poloxamer 407 is a polyoxyethylene polymer and hydrophilic non-ionic surfactant. It consists of a central hydrophobic block of polypropylene glycol that is flanked on each side by polyethylene glycol blocks, both hydrophilic in nature. Poloxamer 407 is used as an emulsifying agent and solubilizing agent in cosmetic and personal products...
Investigational
Matched Description: … It consists of a central hydrophobic block of polypropylene glycol that is flanked on each side by polyethylene ... glycol blocks, both hydrophilic in nature. ... Poloxamer 407 is used as an emulsifying agent and solubilizing agent in cosmetic and personal products …
Matched Categories: … Polyethylene Glycols …

ARX201

ARX201 (PEG-ahGH) is a recombinant form of human growth hormone that has been modified using Ambrx’s patented ReCODE™ technology to achieve precise spatial positioning of the site of polyethylene glycol (PEG) attachment to human growth hormone, by biosynthetic incorporation of a chemically unique amino acid (ahGH). ARX201 has improved pharmacological...
Investigational
Matched Description: … glycol (PEG) attachment to human growth hormone, by biosynthetic incorporation of a chemically unique ... modified using Ambrx’s patented ReCODE™ technology to achieve precise spatial positioning of the site of polyethylene …

Peginterferon alfacon-1

PEGylation is a technology for the chemical attachment of polyethylene glycol (PEG) polymer chains to a broad range of drug substances such as peptides and proteins including antibody fragments; small molecules, and other drugs. [Infergen] is a bio-engineered type I interferon alpha that is FDA-approved for the treatment of patients...
Investigational
Matched Description: … PEGylation is a technology for the chemical attachment of polyethylene glycol (PEG) polymer chains to ... , and other drugs. ... a broad range of drug substances such as peptides and proteins including antibody fragments; small molecules …
Displaying drugs 26 - 50 of 50 in total