Displaying drugs 626 - 650 of 710 in total
QXL138AM
QXL138AM is a masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon alpha 2a. It binds the CD138 protein on the surface of the tumour cells.
Investigational
Matched Synonyms: … Masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon …
Matched Description: … QXL138AM is a masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused …
Matched Description: … QXL138AM is a masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused …
GYM329
GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH-dependent manner
Investigational
Matched Synonyms: … recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH dependent …
Matched Description: … GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin …
Matched Description: … GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin …
Zanidatamab
According to Zymeworks, "ZW25 is a bispecific antibody that can simultaneously bind two non-overlapping epitopes, known as biparatopic binding, of HER2 resulting in dual HER2 signal blockade, increased binding and removal of HER2 protein from the cell surface, and potent effector function. These combined mechanisms of action have led to...
Investigational
Matched Synonyms: … ANTI-HER2 BI-SPECIFIC MONOCLONAL ANTIBODY ZW25 ... TYROSINEPROTEIN KINASE ERBB-2, EGFR2, HER2, HER-2, P185C-ERBB2, NEU, CD340)), HUMANIZED MONOCLONAL ANTIBODY …
Matched Description: … removal of HER2 protein from the cell surface, and potent effector function. ... epitopes, known as biparatopic binding, of HER2 resulting in dual HER2 signal blockade, increased binding and ... combined mechanisms of action have led to significant anti-tumor activity in preclinical models of breast and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … removal of HER2 protein from the cell surface, and potent effector function. ... epitopes, known as biparatopic binding, of HER2 resulting in dual HER2 signal blockade, increased binding and ... combined mechanisms of action have led to significant anti-tumor activity in preclinical models of breast and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Rozrolimupab
Rozrolimupab is a recombinant polyclonal antibody consisting of 25 different anti-Rhesus D (RhD) antibodies to replace existing anti-RhD hyperimmune immunoglobulins for the treatment of Idiopathic Thrombocytopenic Purpura (ITP) and the prevention of Hemolytic Disease of Newborns (HDN).
Investigational
Matched Synonyms: … Recombinant human antigen-specific polyclonal antibody (pAb) against RhD antigen expressed in Chinese …
Matched Description: … anti-RhD hyperimmune immunoglobulins for the treatment of Idiopathic Thrombocytopenic Purpura (ITP) and ... Rozrolimupab is a recombinant polyclonal antibody consisting of 25 different anti-Rhesus D (RhD) antibodies …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … anti-RhD hyperimmune immunoglobulins for the treatment of Idiopathic Thrombocytopenic Purpura (ITP) and ... Rozrolimupab is a recombinant polyclonal antibody consisting of 25 different anti-Rhesus D (RhD) antibodies …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Alnuctamab
Investigational
Matched Synonyms: … immunoglobulin G1 (IgG1)-based, B-cell maturation antigen (BCMA) x CD3 T-cell bispecific monoclonal antibody …
OMS906
OMS906 is a humanized Igg4 monoclonal antibody against mannan-binding lectin-associated serine protease-3 (MASP-3) currently being developed by Omeros.
Investigational
Matched Synonyms: … Humanized immunoglobulin G4 monoclonal antibody directed against mannan-binding lectin-associated serine …
Matched Description: … OMS906 is a humanized Igg4 monoclonal antibody against mannan-binding lectin-associated serine protease …
Matched Description: … OMS906 is a humanized Igg4 monoclonal antibody against mannan-binding lectin-associated serine protease …
Olmesartan
Olmesartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes telmisartan, candesartan, losartan, valsartan, and irbesartan. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of aldosterone...
Approved
Investigational
Matched International brands: … Golme …
Matched Description: … Overall, olmesartan's physiologic effects lead to reduced blood pressure, lower aldosterone levels, reduced ... aldosterone and ADH, cardiac stimulation, and renal reabsorption of sodium, among others. ... and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of …
Matched Mixtures name: … Amlodipine and olmesartan Medoxomil ... Amlodipine and olmesartan Medoxomil ... Amlodipine and olmesartan Medoxomil …
Matched Categories: … olmesartan medoxomil and diuretics ... olmesartan medoxomil and amlodipine ... Angiotensin II Antagonists and Calcium Channel Blockers ... Angiotensin II receptor blockers (ARBs) and diuretics ... olmesartan medoxomil, amlodipine and hydrochlorothiazide …
Matched Description: … Overall, olmesartan's physiologic effects lead to reduced blood pressure, lower aldosterone levels, reduced ... aldosterone and ADH, cardiac stimulation, and renal reabsorption of sodium, among others. ... and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of …
Matched Mixtures name: … Amlodipine and olmesartan Medoxomil ... Amlodipine and olmesartan Medoxomil ... Amlodipine and olmesartan Medoxomil …
Matched Categories: … olmesartan medoxomil and diuretics ... olmesartan medoxomil and amlodipine ... Angiotensin II Antagonists and Calcium Channel Blockers ... Angiotensin II receptor blockers (ARBs) and diuretics ... olmesartan medoxomil, amlodipine and hydrochlorothiazide …
Indatuximab ravtansine
Indatuximab ravtansine is under investigation in clinical trial NCT01001442 (Safety and Dose Determining Multi-dose Study of BT062 in Patients With Relapsed or Refractory Multiple Myeloma).
Investigational
Matched Synonyms: … Deacetyl-N2'-[4-Methyl-4-(Oxobuthyldithio)-1-Oxopentyl]-Maytansine-Chimerized Anti-Cd138 Igg4 Monoclonal Antibody …
Matched Description: … Indatuximab ravtansine is under investigation in clinical trial NCT01001442 (Safety and Dose Determining …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antibody-drug Conjugates …
Matched Description: … Indatuximab ravtansine is under investigation in clinical trial NCT01001442 (Safety and Dose Determining …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antibody-drug Conjugates …
Avobenzone
Avobenzone is dibenzoyl methane derivative. It is oil soluble ingredient. Avobenzone has the ability to absorb ultraviolet light over wider range of wavelengths. It is included in many commercially available sunscreens which are used as wide spectrum sunscreens. Avobenzone is very sensitive to light, to increase its stability and duration...
Approved
Investigational
Matched Description: … Avobenzone is very sensitive to light, to increase its stability and duration of action, photostablizers ... sun, using sunscreen agents may help reduce long-term sun damage such as premature aging of the skin and …
Matched Mixtures name: … Pro-collagen Day and Night Duo ... Ultimate Pro-collagen Day and Night Duo ... Olay Regenerist Day and Night Trial Pack …
Matched Products: … Naked Sundays Golden Glow Body Sunscreen SPF50 100ml …
Matched Mixtures name: … Pro-collagen Day and Night Duo ... Ultimate Pro-collagen Day and Night Duo ... Olay Regenerist Day and Night Trial Pack …
Matched Products: … Naked Sundays Golden Glow Body Sunscreen SPF50 100ml …
Agrostis gigantea top
Agrostis gigantea top is the flowering part of the Agrostis gigantea plant. Agrostis gigantea top is mainly used in allergenic testing.
Approved
Matched Synonyms: … Vilfa nigra top ... Agrostis nigra top …
Ceftriaxone
Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic. It has a very long half-life compared to other cephalosporins and is high penetrable into the meninges , eyes , and inner ear . Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins, but worse activity against methicillin-susceptible S.aureus. Ceftriaxone...
Approved
Matched Description: … [A215582] It has a very long half-life compared to other cephalosporins and is high penetrable into the ... meninges[A215582], eyes[A215647], and inner ear[A215627]. ... Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins …
Matched Products: … Ceftriaxone and Dextrose …
Matched Products: … Ceftriaxone and Dextrose …
Roledumab
Roledumab is under investigation in clinical trial NCT02287896 (Pharmacokinetics and Safety of Roledumab in Rhd-negative Pregnant Women Carrying an Rhd-positive Foetus).
Investigational
Matched Synonyms: … -kappa, anti-(homo sapiens rhd(rhesus blood group d antigen, rhd, cd240d)), homo sapiens monoclonal antibody …
Matched Description: … Roledumab is under investigation in clinical trial NCT02287896 (Pharmacokinetics and Safety of Roledumab …
Matched Description: … Roledumab is under investigation in clinical trial NCT02287896 (Pharmacokinetics and Safety of Roledumab …
Tegoprubart
Investigational
Matched Synonyms: … Humanized Anti-Cd40Lg Igg1, Kappa Monoclonal Antibody With Heavy Chain C220S/C226S/C229S/P238S Substitutions …
Apamistamab iodine I-131
Investigational
Matched Synonyms: … 131I-BC8 monoclonal antibody (Anti-CD45 murine monoclonal antibody radiolabeled with 131I …
Sirexatamab
Investigational
Matched Synonyms: … Anti-dkk-1 monoclonal antibody ly2812176 ... Dkk1-neutralizing monoclonal antibody dkn-01 …
Ambroxol
Ambroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. The substance is a mucoactive drug with several properties including secretolytic and secretomotoric actions that restore the physiological clearance mechanisms of the...
Approved
Investigational
Matched Description: … in providing protection against infection and irritating agents. ... It stimulates synthesis and release of surfactant by type II pneumocytes. ... The substance is a mucoactive drug with several properties including secretolytic and secretomotoric …
Matched Mixtures name: … TROFERIT-FLOW ... TROFERIT-FLOW …
Matched Categories: … Cough and Cold Preparations ... clenbuterol and ambroxol …
Matched Products: … ZERINOL GOLA ... ZERINOL GOLA MENTA ... ZERINOL GOLA RIBES NERO …
Matched Mixtures name: … TROFERIT-FLOW ... TROFERIT-FLOW …
Matched Categories: … Cough and Cold Preparations ... clenbuterol and ambroxol …
Matched Products: … ZERINOL GOLA ... ZERINOL GOLA MENTA ... ZERINOL GOLA RIBES NERO …
Imalumab
Imalumab is under investigation in clinical trial NCT02540356 (Phase 1/2a Two-arm Dose-escalation Study of BAX69 in Subjects With Malignant Ascites of Ovarian Cancer).
Investigational
Matched Synonyms: … migration inhibitory factor, glycosylation-inhibiting factor, glif, gif)), homo sapiens monoclonal antibody …
Efineptakin alfa
Efineptakin alfa (also known as NT-I7) is a long-acting human interleukin-7 (IL-7) fusion protein that promotes T-cell development, contributing to the immune response. Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better bioavailability. This drug is currently being investigated in the areas...
Investigational
Matched Synonyms: … Recombinant human interleukin-7 fused to a hybrid crystallizable fragment region of a human antibody ... Recombinant human interleukin-7 fused to a hybrid crystallizable fragment region of a human antibody …
Matched Description: … Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better ... This drug is currently being investigated in the areas of oncology, immunology, and infectious disease …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better ... This drug is currently being investigated in the areas of oncology, immunology, and infectious disease …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Brentuximab vedotin
Brentuximab vedotin, also known as Adcetris®, is an antibody-drug conjugate that combines an anti-CD30 antibody with the drug monomethyl auristatin E (MMAE). It is an anti-neoplastic agent used in the treatment of Hodgkin's lymphoma and systemic anaplastic large-cell lymphoma. Brentuximab vedotin was initially approved in 2011. In January 2012, the...
Approved
Investigational
Matched Synonyms: … Monoclonal antibody SGN-30 …
Matched Description: … antibody with the drug monomethyl auristatin E (MMAE). ... Brentuximab vedotin, also known as Adcetris®, is an antibody-drug conjugate that combines an anti-CD30 ... Lymphoma may begin anywhere in the body and can spread to nearby lymph nodes. …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Antibody-drug Conjugates ... CD30-directed Antibody Interactions …
Matched Description: … antibody with the drug monomethyl auristatin E (MMAE). ... Brentuximab vedotin, also known as Adcetris®, is an antibody-drug conjugate that combines an anti-CD30 ... Lymphoma may begin anywhere in the body and can spread to nearby lymph nodes. …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Antibody-drug Conjugates ... CD30-directed Antibody Interactions …
STM-217
Investigational
Matched Synonyms: … Soluble receptor fused to part of an antibody that is designed to block the growth factor activin a …
FB-825
FB-825 is an investigational humanized monoclonal antibody that targets the CεmX domain of the membrane-bound IgE (mIgE), causing a depletion of mIgE positive B-cells. It is currently being investigated for immune disorders, such as atopic dermatitis and hyperimmunoglobulin E syndrome (HIES).[A258448,L45743]
Investigational
Matched Synonyms: … Recombinant humanized immunoglobulin gamma 1 monoclonal antibody (mAb) directed against the CemX segment …
Matched Description: … It is currently being investigated for immune disorders, such as atopic dermatitis and hyperimmunoglobulin ... FB-825 is an investigational humanized monoclonal antibody that targets the CεmX domain of the membrane-bound …
Matched Description: … It is currently being investigated for immune disorders, such as atopic dermatitis and hyperimmunoglobulin ... FB-825 is an investigational humanized monoclonal antibody that targets the CεmX domain of the membrane-bound …
Narsoplimab
Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets. Evidence increasingly points to a role for the complement system in TMA.[A241030, A241040] Mannan-associated lectin-binding serine protease-2 (MASP-2) is a major effector in the complement lectin pathway.[A241030,...
Investigational
Matched Synonyms: … MASP-2 antibody ... ANTI-MASP-2 MONOCLONAL ANTIBODY OMS721 ... SERINE PROTEASE 2 (MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASE 2, EC=3.4.21.104) HUMAN MONOCLONAL ANTIBODY …
Matched Description: … uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets ... [A241030, A241040] Narsoplimab (OMS721), a human IgG4λ anti-MASP-2 antibody, is under consideration as ... Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets ... [A241030, A241040] Narsoplimab (OMS721), a human IgG4λ anti-MASP-2 antibody, is under consideration as ... Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Cefuroxime
Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Approved
Matched Description: … It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus …
Matched Categories: … cefuroxime and metronidazole …
Matched Products: … Cefuroxime and Dextrose …
Matched Categories: … cefuroxime and metronidazole …
Matched Products: … Cefuroxime and Dextrose …
Bersanlimab
Bersanlimab is an investigational monoclonal antibody directed against intercellular adhesion molecule 1 (ICAM-1).
Investigational
Matched Synonyms: … Anti-icam-1 monoclonal antibody bi-505 ... lambda, anti-(homo sapiens icam1(intercellular adhesion molecule 1, icam-1, cd54)), human monoclonal antibody …
Matched Description: … Bersanlimab is an investigational monoclonal antibody directed against intercellular adhesion molecule …
Matched Description: … Bersanlimab is an investigational monoclonal antibody directed against intercellular adhesion molecule …
NBL-015
Investigational
Matched Synonyms: … Fully human monoclonal IgG1 antibody against the type 2 isoform of human Claudin 18 protein (Claudin …
Displaying drugs 626 - 650 of 710 in total