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Displaying drugs 701 - 707 of 707 in total
The use of umbilical cord blood (UCB) for therapies is advantageous because of its ease of access, non-invasive collection procedures, and more plasticity for multi-differentiation. UCB contains a large source of hematopoietic stem cells (HSCs) that are capable of self-renewal, have increased sensitivity to various factors, and are able to...
Investigational
Matched Description: … , from red blood cells, to B-, T-, and Natural Killer Cells. ... Specifically, the proliferation capacity of human umbilical cord blood mononuclear progenitor cells ( ... Cord blood transplants have been used to treat conditions from aplastic anemia, B-thalassemia, X-linked …
A synthetic retinoid that is used orally as a chemopreventive against prostate cancer and in women at risk of developing contralateral breast cancer. It is also effective as an antineoplastic agent.
Investigational
Matched Synonyms: … 4-HPR ... 4-hydroxy(phenyl)retinamide ... 4-hydroxyphenyl retinamide …
Matched Iupac: … (2E,4E,6E,8E)-N-(4-hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenamide …
Matched Description: … A synthetic retinoid that is used orally as a chemopreventive against prostate cancer and in women at …
MMDA, or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant and psychedelic properties. It also acts as an entheogen and an entactogen. MMDA bears resemblance to the psychopharmacologically active essential oils elemicin and myristicin found in nutmeg. The effects of MMDA includes feelings of euphoria and warmth,...
Experimental
Illicit
Matched Iupac: … 1-(7-methoxy-2H-1,3-benzodioxol-5-yl)propan-2-amine …
Matched Description: … It also acts as an entheogen and an entactogen. ... or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant and ... The effects of MMDA includes feelings of euphoria and warmth, as well as realistic closed-eye visuals …
Tomaralimab is under investigation in clinical trial NCT01794663 (Placebo-Controlled Study to Evaluate the Safety and Efficacy of OPN-305 in Preventing Delayed Renal Graft Function).
Investigational
Matched Description: … under investigation in clinical trial NCT01794663 (Placebo-Controlled Study to Evaluate the Safety and
Matched Categories: … Amino Acids, Peptides, and Proteins …
INO-4800 is a DNA vaccine containing the full sequence for the SARS-CoV-2 Spike (S) protein in development for immunization against COVID-19. Early in vitro studies using HEK-293T cells demonstrated that the transfection of INO-4800 results in the expression of S protein by human cells.[A214475, A214478] Follow up studies in both...
Investigational
Matched Description: … on June 4, 2020, and expected to start later in the month. ... 293T cells demonstrated that the transfection of INO-4800 results in the expression of S protein by human ... [A214475] A Phase 1 clinical trial for INO-4800 in the U.S. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ezatiostat is investigated in clinical trials for treating myelodysplastic syndrome. This compound belongs to the peptides. These are compounds containing an amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen...
Investigational
Matched Iupac: … ethyl (2S)-2-amino-4-{[(1R)-2-(benzylsulfanyl)-1-{[(1R)-2-ethoxy-2-oxo-1-phenylethyl]carbamoyl}ethyl] …
Matched Description: … Ezatiostat has myelostimulant activity in preclinical rodent models and human bone marrow cultures, and ... Ezatiostat is a small molecule drug that is an analog inhibitor of glutathione S-transferase P1-1. ... differentiates granulocytes and monocytes in HL60 cells. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
GTS-21 (also known as DMBX-A), is a novel, small-molecule, orally active and selective alpha-7 nicotinic acetylcholine (nACh) receptor agonist that has demonstrated memory and cognition enhancement activity in human clinical trials. Athenagen licensed the exclusive rights to the compound and a related library of analogs as part of the acquisition...
Investigational
Matched Description: … in human clinical trials. ... GTS-21 (also known as DMBX-A), is a novel, small-molecule, orally active and selective alpha-7 nicotinic ... acetylcholine (nACh) receptor agonist that has demonstrated memory and cognition enhancement activity …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 701 - 707 of 707 in total