Displaying drugs 176 - 191 of 191 in total
Isoflavone
Isoflavone is a soy phytoestrogen and a biologically active component of several agriculturally important legumes such as soy, peanut, green peas, chick peas and alfalfa . Soybean is an exceptionally rich source of dietary isoflavones, where the average isoflavone content is 1-2 mg/gram . The main soy isoflavones are mostly...
Experimental
Matched Synonyms: … 3-phenyl-4H-1-benzopyran-4-one ... 3-Phenylchromone …
Matched Iupac: … 3-phenyl-4H-chromen-4-one …
Matched Description: … of soy products associated with a reduced incidences of coronary heart disease, atherosclerosis, type ... 2 mg/gram [A33103]. ... Isoflavone is a soy phytoestrogen and a biologically active component of several agriculturally important …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 3-phenyl-4H-chromen-4-one …
Matched Description: … of soy products associated with a reduced incidences of coronary heart disease, atherosclerosis, type ... 2 mg/gram [A33103]. ... Isoflavone is a soy phytoestrogen and a biologically active component of several agriculturally important …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
XmAb 2513
XmAb 2513 is a humanized monoclonal antibody that targets the antigen CD30, a molecule expressed on the surface of a number of tumor cell types. It has been investigated for the treatment of hodgkin’s lymphoma.
Investigational
Matched Description: … XmAb 2513 is a humanized monoclonal antibody that targets the antigen CD30, a molecule expressed on the ... surface of a number of tumor cell types. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
HPV-16 trojan peptide vaccine
HPV-16 trojan peptide vaccine is an investigational cancer immunotherapy consisting of a novel Trojan peptide complex, composed of human papilloma virus 16 (HPV 16) epitopes, to stimulate antigen-specific CD4 and CD8 T cell responses.
Investigational
Matched Description: … peptide complex, composed of human papilloma virus 16 (HPV 16) epitopes, to stimulate antigen-specific ... CD4 and CD8 T cell responses. ... HPV-16 trojan peptide vaccine is an investigational cancer immunotherapy consisting of a novel Trojan …
Hydrocortisone aceponate
Experimental
Vet approved
Matched Iupac: … (1R,3aS,3bS,9aR,9bS,10S,11aS)-1-[2-(acetyloxy)acetyl]-10-hydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH ... ,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl propanoate …
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C8 Inducers ... Cytochrome P-450 CYP3A Inducers …
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C8 Inducers ... Cytochrome P-450 CYP3A Inducers …
Hu-rhEGF-rP64k/Mont
Hu-rhEGF-rP64k/Mont is a therapeutic vaccine composed by an antigen (recombinant human EGF (rhEGF) chemically conjugated to recombinant P64K (rP64K)) and an adjuvant (Montanide ISA51VG) being investigated for the treatment of advanced non-small cell lung cancer (NSCLC).
Investigational
Matched Description: … Hu-rhEGF-rP64k/Mont is a therapeutic vaccine composed by an antigen (recombinant human EGF (rhEGF) chemically ... conjugated to recombinant P64K (rP64K)) and an adjuvant (Montanide ISA51VG) being investigated for the …
MDX-1379
MDX-1379 vaccine consists of two gp100 melanoma peptides. This drug is underinvestigation to treat malignant melanoma.
Investigational
ING-1
ING-1 is a high-affinity, human engineered trade mark monoclonal antibody that recognizes a 40 kilodalton epithelial cell adhesion molecule (EpCAM) glycoprotein that is expressed in high levels on most adenocarcinomas. It is an attractive target for immunotherapy.
Investigational
Matched Name: … ING-1 …
Matched Description: … ING-1 is a high-affinity, human engineered trade mark monoclonal antibody that recognizes a 40 kilodalton …
Matched Description: … ING-1 is a high-affinity, human engineered trade mark monoclonal antibody that recognizes a 40 kilodalton …
NKG2D-ACE2 CAR-NK Cell
These cells are prepared as universal off-the-shelf CAR-NK cells from cord blood with NKG2D-ACE2 proteins engineered as part of the CARs; the cell secretes IL-15 and GM-CSF. Chimeric antigen receptors (CARs) are artificial receptors consisting of an antibody-derived antigen binding domain and transmembrane and signaling domains from T-cell receptor signalling...
Investigational
Matched Description: … inhibiting SARS-Cov-2 infection of type II alveolar epithelial cells. ... The ACE2 is a receptor for SARS-Cov-2, binding to the S-protein of the viral envelope and competitively ... The GM-CSF acts as a neutralizer for the CAR-T cell-mediated cytokine release and neurotoxicity. …
Sibrotuzumab
Sibrotuzumab is a humanized monoclonal antibody directed against fibroblast activation protein (FAP). It is used to treat cancer.
Investigational
Matched Description: … Sibrotuzumab is a humanized monoclonal antibody directed against fibroblast activation protein (FAP). …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
MVA-BN-brachyury-TRICOM vaccine
MVA-BN-brachyury-TRICOM vaccine is an investigational cancer vaccine. It is composed of recombinant vaccinia viral vector, modified vaccinia Ankara-Bavarian Nordic (MVA-BN), encoding the human transcription factor and tumour-associated antigen (TAA) brachyury, and a triad of T-cell co-stimulatory molecules (TRICOM), which is comprised of the three human immune-enhancing co-stimulatory molecules B7-1, ICAM-1...
Investigational
Matched Description: … B7-1, ICAM-1 and LFA-3. ... transcription factor and tumour-associated antigen (TAA) brachyury, and a triad of T-cell co-stimulatory ... recombinant vaccinia viral vector, modified vaccinia Ankara-Bavarian Nordic (MVA-BN), encoding the human …
Viralym-C
Viralym-C is an investigational T-cell immunotherapy developed by ViraCyte. It consists of Human Leukocyte Antigen (HLA)-matched cytomegalovirus (CMV)-specific T lymphocytes. It was granted FDA orphan designation in January 2017 and investigated for the treatment of CMV infection.[A260291, L47241]
Investigational
Matched Description: … It consists of Human Leukocyte Antigen (HLA)-matched cytomegalovirus (CMV)-specific T lymphocytes. ... It was granted FDA orphan designation in January 2017 and investigated for the treatment of CMV infection …
Omburtamab
CD276 (B7-H3) is a B7/CD28 immunoglobulin superfamily member frequently expressed among solid human tumours.[A242487, A242492] Omburtamab, formerly the murine anti-B7-H3 antibody 8H9, and its humanized forms are currently under clinical development for use in various cancers. Omburtamab is under investigation in clinical trial NCT03275402 (131i-omburtamab Radioimmunotherapy for Neuroblastoma Central Nervous...
Investigational
Matched Description: … CD276 (B7-H3) is a B7/CD28 immunoglobulin superfamily member frequently expressed among solid human tumours ... [A242487, A242492] Omburtamab, formerly the murine anti-B7-H3 antibody 8H9, and its humanized forms are …
LV-SMENP Vaccine
LV-SMENP-DC is a vaccine candidate being developed by Shenzhen Geno-Immune Medical Institute that comprises dendritic cells that are modified with lentiviral vector-expressing synthetic minigene which are based on domains of selected viral proteins. This vaccine is also administered with antigen-specific cytotoxic T lymphocytes (CTLs).
As of August 2020, this vaccine...
Investigational
Matched Description: … This vaccine is also administered with antigen-specific cytotoxic T lymphocytes (CTLs). ... LV-SMENP-DC is a vaccine candidate being developed by Shenzhen Geno-Immune Medical Institute that comprises ... As of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials …
COVID19 s-vax loaded autologous dendritic cell vaccine
Dendritic cells (DCs) can be derived and differentiated from peripheral blood mononuclear cells in the presence of specific cytokines and growth factors. These cells are then loaded with antigens produced by a virus or tumor cell and administered as a vaccine.
Dendritic Cells (DCs) are showing potential as natural adjuvants...
Investigational
Matched Description: … The rationale is that loading a DC cell with SARS-Cov-2 antigens and administering it as a vaccine can ... As of May 2020, the company is pursuing a human clinical trial (ChiCTR2000033003) to test the safety ... boost cell responses; they are considered the most powerful antigen-presenting cells, and are able to …
VPM1002
The bacille Calmette-Guérin (BCG) vaccine protects against severe extrapulmonary forms of tuberculosis (TB) but does not adequately protect against pulmonary TB -- the most prevalent form of TB. This recombinant BCG, VPM1002, has been created in response and investigated for preventing pulmonary TB in newborns and TB recurrence in adults...
Investigational
Matched Description: … VPM1002 is a recombinant BCG vaccine candidate expressing listeriolysin and deficient in urease that ... Mycobacterial antigen accessing the cytosol also improves antigen presentation. ... As of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials …
Displaying drugs 176 - 191 of 191 in total