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Displaying drugs 226 - 250 of 308 in total
Skin-derived ABCB5-positive Mesenchymal Stem cells are under investigation in clinical trial NCT04971161 (Allogeneic Abcb5-positive Dermal Mesenchymal Stromal Cells for Treatment of CVU (Phase Iib)).
Investigational
Matched Synonyms: … Skin-derived ABCB5+ Mesenchymal Stem cells …
Matched Name: … Skin-derived ABCB5-positive Mesenchymal Stem cells …
Matched Description: … Skin-derived ABCB5-positive Mesenchymal Stem cells are under investigation in clinical trial NCT04971161 …
The placenta serves many purposes, with one of the many being a bank of mesenchymal stem cells (MSCs). It can be obtained relatively easily as medical waste from which MSCs can be non-invasively extracted and without the ethical issues that come with embryonic stem cells. The placental MSCs (pMSCs) are...
Investigational
Matched Name: … Placental Mesenchymal Stem Cells …
Matched Description: … The placenta serves many purposes, with one of the many being a bank of mesenchymal stem cells (MSCs) ... which MSCs can be non-invasively extracted and without the ethical issues that come with embryonic stem
Umbilical-cord derived MSCs are currently being tested for numerous clinical applications due to their immunosuppressive and anti-inflammatory properties. In comparison to bone-marrow derived MSCs, these cells are more resilient, easier to extract, and generally regarded as less immunogenic. The condition medium (CM) derived from these MSCs has also been implicated...
Investigational
Matched Synonyms: … Allogeneic Human Umbilical Derived Mesenchymal Stem Cells in Conditioned Media ... Allogenic Human Umbilical Derived Mesenchymal Stem Cells in Conditioned Media …
Matched Name: … Allogenic Human Umbilical Derived Mesenchymal Stem Cells in Conditioned Media …
Investigational
Matched Name: … Allogenic fetal mesenchymal stem cells …
Stem cells are self-renewing and proliferate without differentiation, with the two major groups being embryonic stem cells (ESCs) and adult stem cells (ASC). Differentiation occurs under different conditions into different cell types. ESCs are from the inner cell mass of blastocysts while ASCs are deposited into adult tissues with restricted...
Investigational
Matched Name: … Human Menstrual Blood-derived Stem Cells …
Matched Description: … embryonic stem cells (ESCs) and adult stem cells (ASC). ... MenSCs are special compared to older methods of adult stem cell extraction such as bone marrow stem cell ... Because this is a non-invasive way to obtain stem cells, it is simple and easy to obtain the stem cells …
Dammarane type triterpene saponins based mainly on the aglycones, protopanaxadiol and protopanaxatriol.
Experimental
Matched Synonyms: … Ginseng root-neutral saponins ... Neutral saponins of panax ginseng root
Experimental
Matched Synonyms: … Gentian root ... Gentiana lutea root
Investigational
Matched Name: … Human Embryonic Stem Cell-derived Astrocytes …
The use of umbilical cord blood (UCB) for therapies is advantageous because of its ease of access, non-invasive collection procedures, and more plasticity for multi-differentiation. UCB contains a large source of hematopoietic stem cells (HSCs) that are capable of self-renewal, have increased sensitivity to various factors, and are able to...
Investigational
Matched Name: … Umbilical Cord Blood Hematopoietic Stem Cells …
Matched Description: … UCB contains a large source of hematopoietic stem cells (HSCs) that are capable of self-renewal, have …
Autologous non-hematopoietic peripheral blood stem cells have been created into a formulation for use in a clinical trial (NCT04473170) by the Abu Dhabi Stem Cells Center. The cells have the characterizations of CD90+, CD133+, Oct-4+, CD45-, and CD71-.
Investigational
Matched Name: … Autologous Non-Hematopoietic Peripheral Blood Stem Cells …
Matched Description: … in a clinical trial (NCT04473170) by the Abu Dhabi Stem Cells Center. ... Autologous non-hematopoietic peripheral blood stem cells have been created into a formulation for use …
Autologous hematopoietic peripheral blood stem cells were tested in a clinical trial (NCT00424489) by Northwestern University for the treatment of refractory myasthenia gravis.
Investigational
Matched Name: … Autologous Hematopoietic Peripheral Blood Stem Cells …
Matched Description: … Autologous hematopoietic peripheral blood stem cells were tested in a clinical trial (NCT00424489) by …
Investigational
Matched Name: … Allogeneic ABCB5-positive limbal stem cells …
CAStem is composed of immunity- and matrix-regulatory cells (IMRCs), also known as M cells, which can be administered through injection. These IMRCs are differentiated from human embryonic stem cells that are expanded and then harvested. These cells are currently being investigated against lung injury and fibrosis -- conditions which are...
Investigational
Matched Name: … Human Embryonic Stem Cell-derived M Cell …
Matched Description: … These IMRCs are differentiated from human embryonic stem cells that are expanded and then harvested. …
Adipose mesenchymal stem cells (AMSCs) are MSCs derived from adipose tissue, which is more accessible and less painful than stem cells extracted from most other sources. Autologous stem cells are those derived from a patient’s own cells while allogeneic stem cells are derived from that of a donor. Lipoaspiration, also...
Investigational
Matched Name: … Adipose-Derived Mesenchymal Stem Cells: Autologous or Allogeneic Origins …
Matched Description: … Autologous stem cells are those derived from a patient’s own cells while allogeneic stem cells are derived ... and less painful than stem cells extracted from most other sources. ... Adipose mesenchymal stem cells (AMSCs) are MSCs derived from adipose tissue, which is more accessible …
Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase is an investigational lentiviral gene therapy. It comprises autologous CD34+ hematopoietic stem and progenitor cells (HSPCs) that had been genetically modified ex vivo with EFS-ADA LV.
Investigational
Matched Name: … Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase …
Matched Description: … Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase is an investigational ... It comprises autologous CD34+ hematopoietic stem and progenitor cells (HSPCs) that had been genetically …
ORBCEL-C™ is the trade name of a product composed of highly purified stromal cells derived from the human umbilical cord. The isolated cells are expanded in culture and are able to be used allogenically -- meaning that one donor’s cells can be given to other unrelated patients. These cells are...
Investigational
Matched Name: … Allogenic Donor CD362-enriched Human Umbilical Cord-derived Mesenchymal Stem Cells …
Matched Description: … stemness markers with both embryonic stem cells (ESCs) and adult mesenchymal stem cells (MSCs); this ... These cells are CD362 enriched umbilical cord-derived mesenchymal stem cells (UC-MSCs); UC-MSCs share …
CYP-001 is a mesenchymoangioblast (MCA)-derived mesenchymal stem cell (MSC) therapy that originates from the mesoderm. When activated with fibroblast growth factor-2 (FGF-2), MCAs create colonies with specific phenotypes. These cells are then able to differentiate into bone, cartilage, and adipose tissue. The MCA-derived MSCs can be obtained from induced pluripotent...
Investigational
Matched Synonyms: … Mesenchymoangioblast-derived mesenchymal stem cells …
Matched Description: … CYP-001 is a mesenchymoangioblast (MCA)-derived mesenchymal stem cell (MSC) therapy that originates from ... The MCA-derived MSCs can be obtained from induced pluripotent stem cells (iPSCs) and then expanded in …
Holoclar (ex vivo expanded autologous human corneal epithelial cells containing stem cells) is a stem cell therapy used to treat limbal stem cell deficiencies.
Investigational
Matched Name: … Ex vivo expanded autologous human corneal epithelial cells containing stem cells …
Matched Description: … Holoclar (_ex vivo_ expanded autologous human corneal epithelial cells containing stem cells) is a stem ... cell therapy used to treat limbal stem cell deficiencies. …
Investigational
Matched Synonyms: … Cinnamic acid (constituent of cinnamomum verum bark) ... Trans-cinnamic acid (constituent of cinnamomum cassia bark) …
Investigational
Matched Synonyms: … Adult-derived hemangioblast stem cells …
Investigational
Matched Synonyms: … Autologous osteogenic stem cells …
Investigational
Matched Synonyms: … Autologous adipose derived mesenchymal stem cells (MSCS) …
CLZ-2002 consists of allogeneic mesenchymal stem cells derived neuronal regeneration-promoting cells.
Investigational
Matched Synonyms: … allogeneic mesenchymal stem cells derived neuronal regeneration promoting cells …
Matched Description: … CLZ-2002 consists of allogeneic mesenchymal stem cells derived neuronal regeneration-promoting cells. …
EDIT-301 is an investigational cell therapy consisting of autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/CAS12a at the gamma globin gene (HBG1 and HBG2).
Investigational
Matched Synonyms: … Autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/CAS12a at the HBG1 and HBG2 ... autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/Cas12a ribonucleoprotein (RNP …
Matched Description: … EDIT-301 is an investigational cell therapy consisting of autologous CD34+ hematopoietic stem and progenitor …
OTL-203 is an autologous CD34+ enriched cell therapy that contains hematopoietic stem and progenitor cells transduced ex-vivo using a lentiviral vector encoding alpha-L-iduronidase gene.
Investigational
Matched Synonyms: … Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced …
Matched Description: … OTL-203 is an autologous CD34+ enriched cell therapy that contains hematopoietic stem and progenitor …
Displaying drugs 226 - 250 of 308 in total