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Displaying drugs 601 - 625 of 654 in total
Idraparinux, a synthetic pentasaccharide is an antithrombin-dependent inhibitor of activated factor X. It was developed for the treatment and prevention of thromboembolic events. However, clinical trials have revealed that idraparinux had lead to bleeding. As a result, Sanofi stopped the development of the drug.
Investigational
Matched Iupac: … dimethoxy-3-{[(2R,3R,4S,5R,6R)-3,4,5-trimethoxy-6-[(sulfooxy)methyl]oxan-2-yl]oxy}oxane-2-carboxylic acid
Matched Description: … It was developed for the treatment and prevention of thromboembolic events. …
Matched Salts name: … Idraparinux sodium
Experimental
Matched Iupac: … 2-methyl-1,4-dioxo-1,2,3,4-tetrahydronaphthalene-2-sulfonic acid
Matched Salts name: … Menadione sodium bisulfite anhydrous ... Menadione sodium bisulfite trihydrate …
Matched Categories: … Diet, Food, and Nutrition …
An aminoperhydroquinazoline poison found mainly in the liver and ovaries of fishes in the order tetraodontiformes, which are eaten. The toxin causes paresthesia and paralysis through interference with neuromuscular conduction. Tetrodotoxin is being investigated by Wex Pharmaceuticals for the treatment of chronic and breakthrough pain in advanced cancer patients as...
Investigational
Matched Description: … The toxin causes paresthesia and paralysis through interference with neuromuscular conduction. ... Tetrodotoxin is being investigated by Wex Pharmaceuticals for the treatment of chronic and breakthrough ... An aminoperhydroquinazoline poison found mainly in the liver and ovaries of fishes in the order tetraodontiformes …
Matched Categories: … Sodium Channel Blockers …
Investigational
Matched Iupac: … -1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-yl]oxidanesulfonic acid
Matched Salts name: … Larsucosterol sodium
Tianeptine is a drug used primarily in the treatment of major depressive disorder and has been studied in the treatment of irritable bowel syndrome (IBS) . Structurally, it is classified as a tricyclic antidepressant (TCA), however, it possesses different pharmacological properties than typical tricyclic antidepressants . Tianeptine was discovered and...
Investigational
Matched Iupac: … 9lambda6-thia-10-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaen-2-yl}amino)heptanoic acid
Matched Description: … Currently, tianeptine is approved in France and manufactured and marketed by Laboratories Servier SA; ... Tianeptine is a drug used primarily in the treatment of major depressive disorder and has been studied ... Tianeptine was discovered and patented by The French Society of Medical Research in the 1960s [L2946] …
Matched Salts name: … Tianeptine sodium
Fimasartan is an angiotensin II receptor antagonist (ARB) drug employed in the treatment of both hypertension and heart failure. It has been found to be safe when administered with hydrochlorothiazide (a diuretic) in clinical trials. Fimasartan was initially approved September 9th, 2010 in South Korea and is marketed under the...
Investigational
Matched Description: … is an angiotensin II receptor antagonist (ARB) drug employed in the treatment of both hypertension and ... Fimasartan was initially approved September 9th, 2010 in South Korea and is marketed under the brand …
Matched Categories: … fimasartan and diuretics ... fimasartan and amlodipine ... rosuvastatin and fimasartan ... Angiotensin II receptor blockers (ARBs) and diuretics ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers …
Cefovecin is a cephalosporin antibiotic used for the treatment of skin infections in cats and dogs. It is the first single-dose injectable antibiotic for dogs and cats that assures owner compliance with dosing for the animal. It is used for the treatment of skin infections caused by Pasturella multocida in...
Experimental
Vet approved
Matched Iupac: … methoxyimino)acetamido]-8-oxo-3-[(2S)-oxolan-2-yl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Description: … Cefovecin is a cephalosporin antibiotic used for the treatment of skin infections in cats and dogs. ... It is the first single-dose injectable antibiotic for dogs and cats that assures owner compliance with ... It is used for the treatment of skin infections caused by Pasturella multocida in cats, and Staphylococcus …
Matched Salts name: … Cefovecin sodium
Investigational
Matched Iupac: … 3-aminopropane-1-sulfonic acid
Matched Salts name: … Tramiprosate sodium
Investigational
Cefminox (INN) is a second generation cephalosporin antibiotic. It is approved for use in Japan.
Experimental
Matched Iupac: … methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Salts name: … Cefminox sodium ... Cefminox sodium hydrate …
A polyether antibiotic which affects ion transport and ATPase activity in mitochondria. It is produced by Streptomyces hygroscopicus. (From Merck Index, 11th ed)
Experimental
Matched Iupac: … -5-yl]-9-methoxy-2,4,10-trimethyl-1,6-dioxaspiro[4.5]decan-7-yl]methyl}-3-methyloxan-2-yl]propanoic acid
Matched Description: … A polyether antibiotic which affects ion transport and ATPase activity in mitochondria. …
Matched Salts name: … Nigericin sodium
Experimental
Investigational
Matched Iupac: … [3-(N-hydroxyformamido)propyl]phosphonic acid
Matched Salts name: … Fosmidomycin sodium
Experimental
Matched Salts name: … Tenidap sodium
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Strepronin is a mucolytic drug. A mucolytic agent is any agent which dissolves thick mucus usually used to help relieve respiratory difficulties. The viscosity of mucous secretions in the lungs is dependent upon the concentrations of mucoprotein as well as the presence of disulfide bonds between these macromolecules and DNA.
Experimental
Matched Iupac: … 2-[2-(thiophene-2-carbonylsulfanyl)propanamido]acetic acid
Matched Description: … concentrations of mucoprotein as well as the presence of disulfide bonds between these macromolecules and
Matched Salts name: … Stepronin sodium
Matched Categories: … Cough and Cold Preparations ... Amino Acids, Peptides, and Proteins …
Vet approved
Matched Iupac: … bioxolan]-5-yl]-2,8-dimethyl-1,6-dioxaspiro[4.5]decan-7-yl]ethyl]-5-methoxy-3-methyloxan-2-yl]acetic acid
Matched Salts name: … Semduramicin sodium
Acediasulfone (INN) is an antimicrobial and antimalarial long-acting prodrug of dapsone.
Experimental
Matched Iupac: … 2-{[4-(4-aminobenzenesulfonyl)phenyl]amino}acetic acid
Matched Description: … Acediasulfone (INN) is an antimicrobial and antimalarial long-acting prodrug of dapsone. …
Matched Salts name: … Acediasulfone sodium
Briciclib has been used in trials studying the treatment of Lymphoma, Neoplasms, Advanced Solid Tumor, and Acute Lymphocytic Leukemia.
Investigational
Matched Iupac: … (2-methoxy-5-{[(E)-2-(2,4,6-trimethoxyphenyl)ethenesulfonyl]methyl}phenoxy)phosphonic acid
Matched Description: … Briciclib has been used in trials studying the treatment of Lymphoma, Neoplasms, Advanced Solid Tumor, and
Matched Salts name: … Briciclib Sodium
Experimental
Matched Iupac: … )-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Salts name: … Cefodizime sodium
Rigosertib has been used in trials studying the treatment and basic science of MDS, RAEB, Cancer, Hepatoma, and Neoplasms, among others.
Investigational
Matched Iupac: … 2-[(2-methoxy-5-{[(E)-2-(2,4,6-trimethoxyphenyl)ethenesulfonyl]methyl}phenyl)amino]acetic acid
Matched Description: … , and Neoplasms, among others. ... Rigosertib has been used in trials studying the treatment and basic science of MDS, RAEB, Cancer, Hepatoma …
Matched Salts name: … Rigosertib Sodium
Matched Categories: … Amino Acids, Peptides, and Proteins …
A sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine.
Vet approved
Matched Description: … A sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine. …
Matched Salts name: … Sulfachlorpyridazine sodium ... Sodium sulfachlorpyridazine monohydrate …
Denufosol was an inhaled drug used for the treatment of cystic fibrosis (CF), showing various improvements in lung function during a phase III clinical trial. A new drug application (NDA) was filed with the FDA in 2011, however, the second phase III clinical trial showed a lack of improvement in...
Investigational
Matched Iupac: … tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphinic acid
Matched Description: … Denufosol has not gained FDA approval, and clinical trials with this drug have ceased since 2011. ... The drug was also evaluated in the treatment of retinal detachment and other diseases of the retina. …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Investigational
Matched Iupac: … -2-yl)-4H,5H,6H-pyrrolo[1,2-b]pyrazol-3-yl]quinolin-7-yl}oxy)ethoxy]carbonyl}amino)butyl]phosphonic acid
Matched Salts name: … BR-007 sodium
Eritoran is a structural analogue of the lipid A portion of lipopolysaccharide (LPS). It is being developed by Eisai Research Institute of Boston for the treatment of severe sepsis.
Investigational
Matched Iupac: … -11-enamido]-5-(phosphonooxy)oxan-2-yl]oxy}methyl)-3-(3-oxotetradecanamido)oxan-2-yl]oxy}phosphonic acid
Hyperforin is a phytochemical generated by the plants of the Hypericum family. One of the most important members of this family, due to its medical properties, is Hypericum perforatum, also known as St John's wort.
Nutraceutical
Laquinimod is an immunomodulator developed by Active Biotech and produced by Teva Pharmaceutical Industries. It is currently under development in phase III trials for treatment of multiple sclerosis as an oral therapy, like fingolimod. It has been shown to reduce disease activity on magnetic resonance imaging and to be well...
Investigational
Matched Description: … Laquinimod is an immunomodulator developed by Active Biotech and produced by Teva Pharmaceutical Industries ... It has been shown to reduce disease activity on magnetic resonance imaging and to be well tolerated orally …
Matched Salts name: … Laquinimod sodium
Displaying drugs 601 - 625 of 654 in total