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Displaying drugs 10376 - 10400 of 12130 in total
Experimental
Matched Name: … N-(2-AMINOETHYL)-P-CHLOROBENZAMIDE …
Matched Iupac: … 4-chloro-N-(2-hydroxyethyl)benzamide …
Ricolinostat is under investigation for the treatment of Breast Carcinoma and Metastatic Breast Cancer.
Investigational
Matched Iupac: … 7-{[2-(diphenylamino)pyrimidin-5-yl]formamido}-N-hydroxyheptanamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Iupac: … 2-[2,5-bis(aziridin-1-yl)-4-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl]-2-methoxyethyl carbamate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
GC-373 is a peptide aldehyde which is metabolized from the bisulfide adduct, GC-376 free acid[A219031,A219036]. It is an inhibitor of Mpro (otherwise known as 3CLpro), a viral encoded protease that cleaves and activates functional proteins involved in viral replication and transcription . GC-373 has been shown to inhibit the Mpro...
Experimental
Matched Iupac: … benzyl N-[(1S)-3-methyl-1-{[(2S)-1-oxo-3-(2-oxopyrrolidin-3-yl)propan-2-yl]carbamoyl}butyl]carbamate …
Matched Description: … with its prodrug, GC-376, GC-373 was recently investigated _in vitro_ in cell culture against SARS-Cov-2
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Vet approved
Matched Iupac: … ,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate ... 2-[(1R,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-1,10-dihydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H …
Experimental
Matched Iupac: … 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
A sulfhydryl reagent that is widely used in experimental biochemical studies. [PubChem]
Experimental
Matched Iupac: … 1-ethyl-2,5-dihydro-1H-pyrrole-2,5-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Idazoxan has been used in trials studying the basic science of Molecular Imaging, Alzheimer Disease, and Major Depressive Disorder.
Investigational
Matched Iupac: … 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... Adrenergic alpha-2 Receptor Antagonists …
Hemoporfin is under investigation in clinical trial NCT03125057 (A Pilot Study of Hemoporfin PDT in Children With Port-wine Stain).
Investigational
Matched Iupac: … 3-[20-(2-carboxyethyl)-10,15-bis(1-hydroxyethyl)-5,9,14,19-tetramethyl-21,22,23,24-tetraazapentacyclo ... [16.2.1.1^{3,6}.1^{8,11}.1^{13,16}]tetracosa-1,3(24),4,6,8,10,12,14,16(22),17,19-undecaen-4-yl]propanoic …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
PF-07304814 is a small molecule prodrug that targets the 3CLpro protease (Mpro), which is used by viruses like SARS-CoV-2 to assemble and multiply . Once administered through intravenous infusion, the compound is cleaved into PF-00835231 to exert its anti-viral effects . PF-07304814, developed by Pfizer, was first identified during the...
Investigational
Matched Iupac: … [(3S)-3-[(2S)-2-[(4-methoxy-1H-indol-2-yl)formamido]-4-methylpentanamido]-2-oxo-4-[(3S)-2-oxopyrrolidin …
Matched Description: … that targets the 3CLpro protease (Mpro), which is used by viruses like SARS-CoV-2 ... Now, it is being tested regarding the novel SARS-CoV-2 virus, including studies in conjunction with [ …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Experimental
Matched Iupac: … [10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosa-14,17-dien-8-yl]-2-oxoethyl acetate ... 2-[(1S,2S,4R,8S,9S,11S,12S,13R,19S)-19-fluoro-11-hydroxy-6,6,9,13-tetramethyl-16-oxo-5,7-dioxapentacyclo …
Experimental
Matched Name: … 2-Phenylamino-Ethanesulfonic Acid …
Matched Iupac: … 2-(phenylamino)ethane-1-sulfonic acid …
Experimental
Matched Name: … (5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE …
Matched Iupac: … 1-[5-(pyridin-3-yl)furan-2-yl]methanamine …
Experimental
Matched Name: … 4-(2-AMINOETHYL)BENZENESULFONAMIDE …
Matched Iupac: … 4-(2-aminoethyl)benzene-1-sulfonamide …
9-(4-hydroxybutyl)-N2-phenylguanine is a solid. This compound belongs to the hypoxanthines. These are compounds containing the purine derivative 1H-purin-6(9H)-one. 9-(4-hydroxybutyl)-n2-phenylguanine is known to target thymidine kinase.
Experimental
Matched Iupac: … 9-(4-hydroxybutyl)-2-(phenylamino)-6,9-dihydro-1H-purin-6-one …
Experimental
Matched Name: … 2-Dimethylamino-Ethyl-Diphosphate …
Matched Iupac: … ({[2-(dimethylamino)ethoxy](hydroxy)phosphoryl}oxy)phosphonic acid …
Investigational
Experimental
Matched Name: … N-({4-[(2-aminopyridin-4-yl)oxy]-3-fluorophenyl}carbamoyl)-2-(4-fluorophenyl)acetamide …
Matched Iupac: … 1-{4-[(2-aminopyridin-4-yl)oxy]-3-fluorophenyl}-3-[2-(4-fluorophenyl)acetyl]urea …
Experimental
Matched Iupac: … N-{4-[2-(2-{[(tert-butoxy)carbonyl]amino}ethyl)-3-ethoxy-2-(ethoxycarbonyl)-3-oxopropyl]phenyl}sulfamic …
Experimental
Matched Name: … N-{2'-[(4-FLUOROPHENYL)AMINO]-4,4'-BIPYRIDIN-2-YL}-4-METHOXYCYCLOHEXANECARBOXAMIDE …
Matched Iupac: … (1r,4r)-N-{2'-[(4-fluorophenyl)amino]-[4,4'-bipyridin]-2-yl}-4-methoxycyclohexane-1-carboxamide …
Experimental
Matched Name: … N-cyclopropyl-4-methyl-3-{2-[(2-morpholin-4-ylethyl)amino]quinazolin-6-yl}benzamide …
Matched Iupac: … N-cyclopropyl-4-methyl-3-(2-{[2-(morpholin-4-yl)ethyl]amino}quinazolin-6-yl)benzamide …
Experimental
Matched Synonyms: … N-(3-Propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline …
Matched Name: … N-(3-Propylcarbamoyloxirane-2-Carbonyl)-Isoleucyl-Proline …
Matched Iupac: … (2S)-1-[(2S,3S)-2-[(3S)-3-hydroxy-3-(propylcarbamoyl)propanamido]-3-methylpentanoyl]pyrrolidine-2-carboxylic …
Poliglusam, or chitosan, is a linear polysaccharide consisting of D-glucosamine and N-acetyl-D-glucosamine. Naturally-occuring poliglusam is found in the cell walls of fungi, soil and sediments where it is produced from degradation of chitin induced by certain groups of bacteria that produce the enzymes deacetylase or chitosanase enzymes . In comparison,...
Experimental
Investigational
Displaying drugs 10376 - 10400 of 12130 in total