Displaying drugs 11526 - 11550 of 12576 in total
Trefentanil
Trefentanil (A-3665) is a fentanyl analogue opioid developed in 1992. It is more potent and shorter acting than alfentanil. Trefentanil is not used in clinics due to the severity of its respiratory depression, though it is still used in research.
Experimental
Matched Iupac: … N-{1-[2-(4-ethyl-5-oxo-4,5-dihydro-1H-1,2,3,4-tetrazol-1-yl)ethyl]-4-phenylpiperidin-4-yl}-N-(2-fluorophenyl …
Radotinib
Radotinib is under investigation for the treatment of Leukemia, Myelogenous, Chronic, BCR-ABL Positive.
Investigational
Matched Iupac: … 4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-{[4-(pyrazin-2-yl)pyrimidin-2- …
Nicofuranose
Experimental
Matched Iupac: … [(2R,3S,4R,5R)-2-hydroxy-3,4-bis(pyridine-3-carbonyloxy)-5-[(pyridine-3-carbonyloxy)methyl]oxolan-2-yl ... ]methyl pyridine-3-carboxylate …
Altropane I-123
Altropane I-123 is under investigation in clinical trial NCT01950468 (A Cross-Over, Multi-Center Trial to Evaluate the Diagnostic Efficacy and Safety of [123I]NAV5001 as an Imaging Agent to Aid in the Diagnosis of Parkinsonian Syndromes).
Investigational
Matched Iupac: … methyl (1R,2S,3S,5S)-3-(4-fluorophenyl)-8-[(2E)-3-(¹²³I)iodoprop-2-en-1-yl]-8-azabicyclo[3.2.1]octane ... -2-carboxylate …
Motexafin lutetium
Motexafin lutetium (MLu) is a second-generation photosensitizer for photodynamic therapy (PDT) of cancer. It belongs to the family of drugs called metallotexaphyrins. Also called lutetium texaphyrin. Motexafin lutetium is a pentadentate aromatic metallotexaphyrin with photosensitizing properties.
Investigational
Matched Iupac: … lutetium(3+) 4,5-diethyl-9,24-bis(3-hydroxypropyl)-16,17-bis({2-[2-(2-methoxyethoxy)ethoxy]ethoxy})-10,23 ... -dimethyl-13,20,25,26,27-pentaazapentacyclo[20.2.1.1^{3,6}.1^{8,11}.0^{14,19}]heptacosa-1,3,5,7,9,11( …
Motexafin gadolinium
Motexafin gadolinium is studied in the treatment of cancer by Pharmacyclics. It may make tumor cells more sensitive to radiation therapy, improve tumor images using magnetic resonance imaging (MRI), and kill cancer cells. It belongs to the family of drugs called metalloporphyrin complexes. Also called gadolinium texaphyrin.
Investigational
Matched Iupac: … gadolinium(3+) 4,5-diethyl-9,24-bis(3-hydroxypropyl)-16,17-bis({2-[2-(2-methoxyethoxy)ethoxy]ethoxy}) ... -10,23-dimethyl-13,20,25,26,27-pentaazapentacyclo[20.2.1.1^{3,6}.1^{8,11}.0^{14,19}]heptacosa-1(25),2,4,6,8 …
Sisomicin
Sisomicin has been used in trials studying the treatment of Pyoderma.
Investigational
Matched Iupac: … (2R,3R,4R,5R)-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran ... -2-yl]oxy}-2-hydroxycyclohexyl]oxy}-5-methyl-4-(methylamino)oxane-3,5-diol …
Cellotetraose
Experimental
Matched Iupac: … ,4R,5R,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}oxan-3-yl]oxy}-4,5-dihydroxy-2-(hydroxymethyl ... )oxan-3-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol ... (2S,3R,4S,5S,6R)-2-{[(2R,3S,4R,5R,6S)-6-{[(2R,3S,4R,5R,6S)-4,5-dihydroxy-2-(hydroxymethyl)-6-{[(2R,3S …
7-methyl-guanosine-5'-triphosphate-5'-guanosine
Experimental
Matched Iupac: … 2-amino-9-[(2R,3R,4S,5R)-5-({[({[({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3,4-dihydroxyoxolan ... -2-yl]-7-methyl-6-oxo-6,7-dihydro-3H-9lambda5-purin-9-ylium ... -2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl)-3,4-dihydroxyoxolan …
Nz-(Dicarboxymethyl)Lysine
Experimental
Matched Iupac: … 2-{[(5S)-5-amino-5-carboxypentyl]amino}propanedioic acid …
Phosphonotyrosine
An amino acid that occurs in endogenous proteins. Tyrosine phosphorylation and dephosphorylation plays a role in cellular signal transduction and possibly in cell growth control and carcinogenesis. [PubChem]
Experimental
Matched Iupac: … (2S)-2-amino-3-[4-(phosphonooxy)phenyl]propanoic acid …
Para-Iodo-D-Phenylalanine Hydroxamic Acid
Experimental
Matched Iupac: … (2R)-2-amino-N-hydroxy-3-(4-iodophenyl)propanamide …
(4s)-5-Fluoro-L-Leucine
Experimental
Matched Iupac: … (2S,4S)-2-amino-5-fluoro-4-methylpentanoic acid …
4-Deoxy-D-Glucuronic Acid
Experimental
Matched Iupac: … (2S,4S,5R,6R)-4,5,6-trihydroxyoxane-2-carboxylic acid …
Alanosine
An amino acid analogue and antibiotic derived from the bacterium Streptomyces alanosinicus with antimetabolite and potential antineoplastic activities.
Investigational
Matched Iupac: … (2S)-2-amino-3-[hydroxy(nitroso)amino]propanoic acid …
N-[(1S)-1-(aminocarbonyl)-4-(ethanimidoylamino)butyl]benzamide
Experimental
Matched Iupac: … (2S)-5-[(E)-(1-aminoethylidene)amino]-2-(phenylformamido)pentanamide …
[4-(4-PHENYL-PIPERIDIN-1-YL)-BENZENESULFONYLAMINO]-ACETIC ACID
Experimental
Matched Iupac: … 2-[4-(4-phenylpiperidin-1-yl)benzenesulfonamido]acetic acid …
4-(4-STYRYL-PHENYLCARBAMOYL)-BUTYRIC ACID
Experimental
Matched Iupac: … 4-({4-[(1E)-2-phenylethenyl]phenyl}carbamoyl)butanoic acid …
Spaglumic acid
Spaglumic acid is the β-aspartyl isoform of N-Acetyl-l-aspartylglutamate (isospaglumic Acid is N-(N-Acetyl-l-α-aspartyl)-l-glutamic acid). In eye drops, spaglumic acid is either a magnesium or sodium salt of N-Acetyl-l-aspartylglutamate. Spaglumic acid is a mast cell stabilizer. Thus it is used in allergic conditions such as allergic conjunctivitis. Specifically spaglumic acid is approved...
Experimental
Matched Iupac: … (2S)-2-[(3S)-3-carboxy-3-acetamidopropanamido]pentanedioic acid …
Glafenine
An anthranilic acid derivative with analgesic properties used for the relief of all types of pain. Glafenine is withdrawn from the American market.
Withdrawn
Matched Iupac: … 2,3-dihydroxypropyl 2-[(7-chloroquinolin-4-yl)amino]benzoate …
Imidafenacin
Imidafenacin is an antispasmodic agent with anticholinergic effects. It antagonizes muscarinic receptors in the bladder to reduce the frequency of urination in the treatment of overactive bladder. It is marketed in Japan under the tradenames Staybla by Ono Pharmaceutical and Uritos by Kyojin Pharmaceutical.
Investigational
Matched Iupac: … 4-(2-methyl-1H-imidazol-1-yl)-2,2-diphenylbutanamide …
Displaying drugs 11526 - 11550 of 12576 in total