Tretinoin.

Article Details

Citation

Copy to clipboard

Yoham AL, Casadesus D

Tretinoin.

.

PubMed ID

32491410 [ View in PubMed

]

Abstract

Tretinoin is a valuable medication in treating mild, moderate, and severe acne that can be used topically or systemically. Tretinoin is also used systemically in the management of acute promyelocytic leukemia (APL). Tretinoin is a vitamin A derivate in the retinoids class of medications. This activity outlines and reviews the indications, actions, and contraindications of tretinoin as a valuable agent in treating acne vulgaris and APL management and therapy. This activity will highlight the mechanism of action, adverse event profile, and other key factors such as off-label uses, including some indications of APL, pre-malignant and malignant skin conditions, and other common skin conditions such as psoriasis, dosing of both oral and topical treatment options, monitoring of both topical and oral tretinoin use (i.e., with emphasis on reliable contraception) pertinent for members of the interprofessional team and healthcare team in the treatment of mild, moderate, severe acne and acute promyelocytic leukemia and related conditions.

DrugBank Data that Cites this Article

Drugs

Tretinoin

Drug Interactions

• Approved
• Vet approved
• Nutraceutical
• Illicit
• Withdrawn
• Investigational
• Experimental
• All Drugs

Drugs	Interaction
Integrate drug-drug interactions in your software
Tretinoin Indomethacin	The risk or severity of elevated intracranial pressure can be increased when Indomethacin is combined with Tretinoin.
Tretinoin Linezolid	The risk or severity of elevated intracranial pressure can be increased when Linezolid is combined with Tretinoin.
Tretinoin Sulfasalazine	The risk or severity of elevated intracranial pressure can be increased when Sulfasalazine is combined with Tretinoin.
Tretinoin Vilanterol	The risk or severity of elevated intracranial pressure can be increased when Vilanterol is combined with Tretinoin.
Tretinoin Tepoxalin	The risk or severity of elevated intracranial pressure can be increased when Tepoxalin is combined with Tretinoin.

Food Interactions

Drug	Interaction
Tretinoin	Take with food. Effect of food on tretinoin absorption is unclear, but food increases the bioavailability of retinoids drug class.