Gonadotropins

Name
Gonadotropins
Accession Number
DBCAT000107
Description

Hormones that stimulate gonadal functions such as GAMETOGENESIS and sex steroid hormone production in the OVARY and the TESTIS. Major gonadotropins are glycoproteins produced primarily by the adenohypophysis (GONADOTROPINS, PITUITARY) and the placenta (CHORIONIC GONADOTROPIN). In some species, pituitary PROLACTIN and PLACENTAL LACTOGEN exert some luteotropic activities.

ATC Classification
Drugs
DrugDrug Description
Lutropin alfaA form of recombinant human luteinizing hormone used to treat female infertility due to hypothalamic or pituitary insufficiency, or due to profound luteinizing hormone deficiency.
UrofollitropinA form of purified human follicle stimulating hormone used to treat infertility in females by inducing follicle development in women without primary ovarian failure.
Chorionic Gonadotropin (Human)A naturally-occurring hormone produced during human placenta used for the treatment of prepubertal cryptorchidism and hypogonadotropic hypogonadism in selected males, and induction of pregnancy in selected infertile women.
FollitropinA form of recombinant human follicle stimulating hormone used to stimulate follicle development in women with primary ovarian hypogonadism and in men with hypogonadotropic hypogonadism.
Corifollitropin alfaA FSH analogue indicated for Controlled Ovarian Stimulation (COS) in combination with a GnRH antagonist for the development of multiple follicles in women participating in an Assisted Reproductive Technology (ART) program.
MenotropinsA purified combination of human luteinizing hormone and follicle stimulating hormone used to treat female infertility.
Choriogonadotropin alfaA recombinant form of human chorionic gonadotropin used to treat female infertility by inducing ovulation.
Luteinizing hormoneNot Annotated
LeuprolideA protein-based luteinizing hormone agonist used to treat prostate cancer, endometriosis, and precocious puberty.
Drugs & Drug Targets
DrugTargetType
Lutropin alfaLutropin-choriogonadotropic hormone receptortarget
UrofollitropinFollicle-stimulating hormone receptortarget
Chorionic Gonadotropin (Human)Lutropin-choriogonadotropic hormone receptortarget
FollitropinFollicle-stimulating hormone receptortarget
Corifollitropin alfaFollicle-stimulating hormone receptortarget
MenotropinsFollicle-stimulating hormone receptortarget
MenotropinsLutropin-choriogonadotropic hormone receptortarget
Choriogonadotropin alfaFollicle-stimulating hormone receptortarget
Choriogonadotropin alfaLutropin-choriogonadotropic hormone receptortarget
LeuprolideGonadotropin-releasing hormone receptortarget
LeuprolideCytochrome P450 3A4enzyme