Hydantoins

Compounds based on imidazolidine dione. Some derivatives are ANTICONVULSANTS.
DrugDrug NameDrug Description
DB00252PhenytoinAn anticonvulsant drug used in the prophylaxis and control of various types of seizures.
DB01320FosphenytoinAn antiepileptic agent used for the management of generalized convulsive status epilepticus and prevention and treatment of seizures occurring during neurosurgery.
DB00532MephenytoinA phenylhydantoin used to treat refractory partial epilepsy.
DB01219DantroleneA direct-acting skeletal muscle relaxant used for the treatment of management of the fulminant hypermetabolism of skeletal muscle leading to malignant hyperthermia crisis.
DB08899EnzalutamideAn androgen receptor inhibitor used to treat castration-resistant prostate cancer.
DB11100AllantoinAn ingredient used in skin care products to relieve irritation and protect minor cuts, scrapes, and burns.
DB00754EthotoinA hydantoin antiepileptic used to control tonic-clonic and complex partial seizures.
DB13396NeocitrullamonNot Annotated
DrugDrug NameTargetType
DB00252PhenytoinSodium channel protein type 5 subunit alphatarget
DB00252PhenytoinSodium channel protein type 1 subunit alphatarget
DB00252PhenytoinCytochrome P450 2C8enzyme
DB00252PhenytoinCytochrome P450 2C19enzyme
DB00252PhenytoinCytochrome P450 2C9enzyme
DB00252PhenytoinCytochrome P450 2B6enzyme
DB00252PhenytoinCytochrome P450 3A5enzyme
DB00252PhenytoinSerum albumincarrier
DB00252PhenytoinCytochrome P450 3A4enzyme
DB00252PhenytoinSolute carrier organic anion transporter family member 1C1transporter
DB00252PhenytoinP-glycoprotein 1transporter
DB00252PhenytoinCanalicular multispecific organic anion transporter 1transporter
DB00252PhenytoinCytochrome P450 11B1, mitochondrialenzyme
DB00252PhenytoinCytochrome P450 3A7enzyme
DB00252PhenytoinNuclear receptor subfamily 1 group I member 2target
DB00252PhenytoinSodium channel subunit beta-1target
DB00252PhenytoinSodium channel protein type 3 subunit alphatarget
DB00252PhenytoinUDP-glucuronosyltransferase 1-1enzyme
DB00252PhenytoinUDP-glucuronosyltransferase 1-6enzyme
DB00252PhenytoinUDP-glucuronosyltransferase 1-9enzyme
DB00252PhenytoinThyroxine-binding globulincarrier
DB00252PhenytoinPotassium voltage-gated channel subfamily H member 2target
DB00252PhenytoinVoltage-dependent L-type calcium channeltarget
DB00252PhenytoinSodium channel protein type 2 subunit alphatarget
DB00252PhenytoinSodium channel protein type 8 subunit alphatarget
DB00252PhenytoinGABA-A receptor (anion channel)target
DB00252PhenytoinCytochrome P450 1A2enzyme
DB00252PhenytoinCytochrome P450 2A6enzyme
DB00252PhenytoinCytochrome P450 2D6enzyme
DB00252PhenytoinCytochrome P450 2E1enzyme
DB00252PhenytoinEpoxide hydrolase 1enzyme
DB00252PhenytoinUDP-glucuronosyltransferase 1-4enzyme
DB00252PhenytoinCatechol O-methyltransferaseenzyme
DB00252PhenytoinNAD(P)H dehydrogenase [quinone] 1enzyme
DB00252PhenytoinCytochrome P450 2C18enzyme
DB01320FosphenytoinSodium channel protein type 5 subunit alphatarget
DB01320FosphenytoinCytochrome P450 2C19enzyme
DB01320FosphenytoinCytochrome P450 2B6enzyme
DB01320FosphenytoinCytochrome P450 2C9enzyme
DB01320FosphenytoinCytochrome P450 3A4enzyme
DB01320FosphenytoinSerum albumincarrier
DB01320FosphenytoinCytochrome P450 1A2enzyme
DB01320FosphenytoinUDP-glucuronosyltransferase 1-6enzyme
DB01320FosphenytoinUDP-glucuronosyltransferase 1-9enzyme
DB01320FosphenytoinThyroxine-binding globulincarrier
DB00532MephenytoinSodium channel protein type 5 subunit alphatarget
DB00532MephenytoinCytochrome P450 2B6enzyme
DB00532MephenytoinCytochrome P450 2C9enzyme
DB00532MephenytoinCytochrome P450 2C19enzyme
DB00532MephenytoinCytochrome P450 1A2enzyme
DB00532MephenytoinCytochrome P450 2D6enzyme
DB00532MephenytoinCytochrome P450 2C8enzyme
DB00532MephenytoinNuclear receptor subfamily 1 group I member 2target
DB00532MephenytoinThyroxine-binding globulincarrier
DB01219DantroleneRyanodine receptor 1target
DB01219DantroleneThyroxine-binding globulincarrier
DB08899EnzalutamideSerum albumincarrier
DB08899EnzalutamideCytochrome P450 2C8enzyme
DB08899EnzalutamideCytochrome P450 3A4enzyme
DB08899EnzalutamideAndrogen receptortarget
DB08899EnzalutamideCytochrome P450 2C9enzyme
DB08899EnzalutamideCytochrome P450 2C19enzyme
DB08899EnzalutamideCytochrome P450 2B6enzyme
DB08899EnzalutamideCytochrome P450 3A5enzyme
DB08899EnzalutamideP-glycoprotein 1transporter
DB08899EnzalutamideThyroxine-binding globulincarrier
DB11100AllantoinThyroxine-binding globulincarrier
DB00754EthotoinSodium channel protein type 5 subunit alphatarget
DB00754EthotoinNuclear receptor subfamily 1 group I member 2target
DB00754EthotoinThyroxine-binding globulincarrier
DB13396NeocitrullamonThyroxine-binding globulincarrier