Carcinogens

Name
Carcinogens
Accession Number
DBCAT000622
Description

Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.

Drugs
DrugDrug Description
DiethylstilbestrolUsed in the treatment of prostate cancer. Previously used in the prevention of miscarriage or premature delivery in pregnant women prone to miscarriage or premature delivery.
Calyculin ANot Available
BromoformNot Available
UrethaneUrethane, formerly marketed as an inactive ingredient in Profenil injection, was determined to be carcinogenic and was removed from the Canadian, US, and UK markets in 1963.
AnilineAniline, phenylamine or aminobenzene is an organic compound with the formula C6H5NH2. Consisting of an amine attached to a benzene ring, aniline is the prototypical aromatic amine. Being a precursor...
CarbazoleNot Available
CiprofibrateNot Annotated
Phenethyl IsothiocyanatePhenethyl Isothiocyanate has been used in trials studying the prevention and treatment of Leukemia, Lung Cancer, Tobacco Use Disorder, and Lymphoproliferative Disorders.
Bisphenol A diglycidyl etherNot Annotated
2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridinePhIP (2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine) has been used in trials studying the basic science of Pancreas Cancer.
Drugs & Drug Targets
DrugTargetType
DiethylstilbestrolEstrogen receptor alphatarget
DiethylstilbestrolEstrogen-related receptor gammatarget
DiethylstilbestrolTransthyretincarrier
DiethylstilbestrolCatechol O-methyltransferaseenzyme
DiethylstilbestrolCytochrome P450 19A1enzyme
DiethylstilbestrolATP-binding cassette sub-family G member 2transporter
DiethylstilbestrolP-glycoprotein 1transporter
DiethylstilbestrolEstrogen receptor betatarget
DiethylstilbestrolCytochrome P450 3A4enzyme
DiethylstilbestrolCytochrome P450 2C8enzyme
DiethylstilbestrolCytochrome P450 2C9enzyme
DiethylstilbestrolCytochrome P450 2E1enzyme
DiethylstilbestrolSteroid hormone receptor ERR1target
DiethylstilbestrolSteroid hormone receptor ERR2target
DiethylstilbestrolNuclear receptor coactivator 2target
DiethylstilbestrolNuclear receptor subfamily 1 group I member 2target
DiethylstilbestrolAndrogen receptortarget
DiethylstilbestrolSex hormone-binding globulintarget
DiethylstilbestrolSolute carrier organic anion transporter family member 1B1transporter
DiethylstilbestrolSolute carrier organic anion transporter family member 2B1transporter
DiethylstilbestrolBile salt export pumptransporter
Calyculin ASerine/threonine-protein phosphatase PP1-gamma catalytic subunittarget
UrethaneCytosolic phospholipase A2enzyme
UrethaneMyeloperoxidaseenzyme
UrethaneAldehyde oxidaseenzyme
AnilineCytochrome P450 2E1enzyme
AnilineKallikrein-1target
AnilineSerum albumintarget
CarbazoleFerredoxin CarActarget
CarbazoleTerminal oxygenase component of carbazoletarget
CiprofibratePeroxisome proliferator-activated receptor alphatarget
Phenethyl IsothiocyanateActin, aortic smooth muscletarget
Phenethyl IsothiocyanateActin, cytoplasmic 1target
Phenethyl IsothiocyanateATP synthase subunit beta, mitochondrialtarget
Phenethyl IsothiocyanateATP synthase subunit e, mitochondrialtarget
Phenethyl IsothiocyanateATP synthase subunit g, mitochondrialtarget
Phenethyl IsothiocyanateCytochrome b5 type Btarget
Phenethyl IsothiocyanateDiablo homolog, mitochondrialtarget
Phenethyl IsothiocyanateF-box only protein 41target
Phenethyl IsothiocyanateHeterogeneous nuclear ribonucleoprotein Ftarget
Phenethyl IsothiocyanateHeterogeneous nuclear ribonucleoprotein Ktarget
Phenethyl IsothiocyanateHeat shock 70 kDa protein 4target
Phenethyl IsothiocyanateHeat shock protein beta-1target
Phenethyl Isothiocyanate10 kDa heat shock protein, mitochondrialtarget
Phenethyl IsothiocyanateHeat shock protein 105 kDatarget
Phenethyl IsothiocyanateNADH-ubiquinone oxidoreductase chain 1target
Phenethyl IsothiocyanateNuclear migration protein nudCtarget
Phenethyl IsothiocyanatePappalysin-1target
Phenethyl IsothiocyanateProteasome subunit alpha type-3target
Phenethyl Isothiocyanate26S protease regulatory subunit 6Atarget
Phenethyl IsothiocyanateRan-specific GTPase-activating proteintarget
Phenethyl IsothiocyanateProtein S100-A10target
Phenethyl IsothiocyanateSplicing factor 3A subunit 3target
Phenethyl IsothiocyanateSWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1target
Phenethyl IsothiocyanateSuccinyl-CoA ligase [GDP-forming] subunit beta, mitochondrialtarget
Phenethyl IsothiocyanateTumor protein D54target
Phenethyl IsothiocyanateTropomyosin alpha-1 chaintarget
Phenethyl IsothiocyanateTropomyosin alpha-3 chaintarget
Phenethyl IsothiocyanateTropomyosin alpha-4 chaintarget
Phenethyl IsothiocyanateTubulin alpha-1A chaintarget
Phenethyl IsothiocyanateTubulin alpha-3C/D chaintarget
Phenethyl IsothiocyanateTubulin alpha-4A chaintarget
Phenethyl IsothiocyanateTubulin beta-1 chaintarget
Phenethyl IsothiocyanateTubulin beta-2A chaintarget
Phenethyl IsothiocyanateTubulin beta-3 chaintarget
Phenethyl IsothiocyanateTubulin beta-4B chaintarget
Phenethyl IsothiocyanateThioredoxintarget
Phenethyl IsothiocyanateUbiquitin carboxyl-terminal hydrolase isozyme L1target
Phenethyl IsothiocyanateUbiquitin carboxyl-terminal hydrolase 14target
Phenethyl IsothiocyanateTransitional endoplasmic reticulum ATPasetarget
Phenethyl IsothiocyanateVimentintarget
Phenethyl Isothiocyanate14-3-3 protein beta/alphatarget
Phenethyl Isothiocyanate14-3-3 protein epsilontarget
Phenethyl Isothiocyanate14-3-3 protein etatarget
Phenethyl Isothiocyanate14-3-3 protein thetatarget
Phenethyl Isothiocyanate14-3-3 protein zeta/deltatarget
2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridineEstrogen receptor alphatarget
2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridineNuclear receptor coactivator 2target