Carcinogens

Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.
DrugDrug NameDrug Indication
DB00255DiethylstilbestrolUsed in the treatment of prostate cancer. Previously used in the prevention of miscarriage or premature delivery in pregnant women prone to miscarriage or premature delivery.
DB02860Calyculin ANot Available
DB03054BromoformNot Available
DB04827UrethaneNot Available
DB06728AnilineNot Available
DB073019H-CARBAZOLENot Available
DB09064CiprofibrateNot Available
DB12695Phenethyl IsothiocyanateNot Available
DB14083Bisphenol A diglycidyl etherNot Available
DB083982-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridineNot Available
DrugDrug NameTargetType
DB00255DiethylstilbestrolEstrogen receptor alphatarget
DB00255DiethylstilbestrolEstrogen-related receptor gammatarget
DB00255DiethylstilbestrolTransthyretincarrier
DB00255DiethylstilbestrolCatechol O-methyltransferaseenzyme
DB00255DiethylstilbestrolCytochrome P450 19A1enzyme
DB00255DiethylstilbestrolATP-binding cassette sub-family G member 2transporter
DB00255DiethylstilbestrolP-glycoprotein 1transporter
DB00255DiethylstilbestrolEstrogen receptor betatarget
DB00255DiethylstilbestrolCytochrome P450 3A4enzyme
DB00255DiethylstilbestrolCytochrome P450 2C8enzyme
DB00255DiethylstilbestrolCytochrome P450 2C9enzyme
DB00255DiethylstilbestrolCytochrome P450 2E1enzyme
DB00255DiethylstilbestrolSteroid hormone receptor ERR1target
DB00255DiethylstilbestrolSteroid hormone receptor ERR2target
DB00255DiethylstilbestrolNuclear receptor coactivator 2target
DB00255DiethylstilbestrolNuclear receptor subfamily 1 group I member 2target
DB00255DiethylstilbestrolAndrogen receptortarget
DB00255DiethylstilbestrolSex hormone-binding globulintarget
DB00255DiethylstilbestrolSolute carrier organic anion transporter family member 1B1transporter
DB00255DiethylstilbestrolSolute carrier organic anion transporter family member 2B1transporter
DB00255DiethylstilbestrolBile salt export pumptransporter
DB02860Calyculin ASerine/threonine-protein phosphatase PP1-gamma catalytic subunittarget
DB04827UrethaneCytosolic phospholipase A2enzyme
DB04827UrethaneMyeloperoxidaseenzyme
DB04827UrethaneAldehyde oxidaseenzyme
DB06728AnilineCytochrome P450 2E1enzyme
DB06728AnilineKallikrein-1target
DB06728AnilineSerum albumintarget
DB073019H-CARBAZOLEFerredoxin CarActarget
DB073019H-CARBAZOLETerminal oxygenase component of carbazoletarget
DB09064CiprofibratePeroxisome proliferator-activated receptor alphatarget
DB12695Phenethyl IsothiocyanateActin, aortic smooth muscletarget
DB12695Phenethyl IsothiocyanateActin, cytoplasmic 1target
DB12695Phenethyl IsothiocyanateATP synthase subunit beta, mitochondrialtarget
DB12695Phenethyl IsothiocyanateATP synthase subunit e, mitochondrialtarget
DB12695Phenethyl IsothiocyanateATP synthase subunit g, mitochondrialtarget
DB12695Phenethyl IsothiocyanateCytochrome b5 type Btarget
DB12695Phenethyl IsothiocyanateDiablo homolog, mitochondrialtarget
DB12695Phenethyl IsothiocyanateF-box only protein 41target
DB12695Phenethyl IsothiocyanateHeterogeneous nuclear ribonucleoprotein Ftarget
DB12695Phenethyl IsothiocyanateHeterogeneous nuclear ribonucleoprotein Ktarget
DB12695Phenethyl IsothiocyanateHeat shock 70 kDa protein 4target
DB12695Phenethyl IsothiocyanateHeat shock protein beta-1target
DB12695Phenethyl Isothiocyanate10 kDa heat shock protein, mitochondrialtarget
DB12695Phenethyl IsothiocyanateHeat shock protein 105 kDatarget
DB12695Phenethyl IsothiocyanateNADH-ubiquinone oxidoreductase chain 1target
DB12695Phenethyl IsothiocyanateNuclear migration protein nudCtarget
DB12695Phenethyl IsothiocyanatePappalysin-1target
DB12695Phenethyl IsothiocyanateProteasome subunit alpha type-3target
DB12695Phenethyl Isothiocyanate26S protease regulatory subunit 6Atarget
DB12695Phenethyl IsothiocyanateRan-specific GTPase-activating proteintarget
DB12695Phenethyl IsothiocyanateProtein S100-A10target
DB12695Phenethyl IsothiocyanateSplicing factor 3A subunit 3target
DB12695Phenethyl IsothiocyanateSWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1target
DB12695Phenethyl IsothiocyanateSuccinyl-CoA ligase [GDP-forming] subunit beta, mitochondrialtarget
DB12695Phenethyl IsothiocyanateTumor protein D54target
DB12695Phenethyl IsothiocyanateTropomyosin alpha-1 chaintarget
DB12695Phenethyl IsothiocyanateTropomyosin alpha-3 chaintarget
DB12695Phenethyl IsothiocyanateTropomyosin alpha-4 chaintarget
DB12695Phenethyl IsothiocyanateTubulin alpha-1A chaintarget
DB12695Phenethyl IsothiocyanateTubulin alpha-3C/D chaintarget
DB12695Phenethyl IsothiocyanateTubulin alpha-4A chaintarget
DB12695Phenethyl IsothiocyanateTubulin beta-1 chaintarget
DB12695Phenethyl IsothiocyanateTubulin beta-2A chaintarget
DB12695Phenethyl IsothiocyanateTubulin beta-3 chaintarget
DB12695Phenethyl IsothiocyanateTubulin beta-4B chaintarget
DB12695Phenethyl IsothiocyanateThioredoxintarget
DB12695Phenethyl IsothiocyanateUbiquitin carboxyl-terminal hydrolase isozyme L1target
DB12695Phenethyl IsothiocyanateUbiquitin carboxyl-terminal hydrolase 14target
DB12695Phenethyl IsothiocyanateTransitional endoplasmic reticulum ATPasetarget
DB12695Phenethyl IsothiocyanateVimentintarget
DB12695Phenethyl Isothiocyanate14-3-3 protein beta/alphatarget
DB12695Phenethyl Isothiocyanate14-3-3 protein epsilontarget
DB12695Phenethyl Isothiocyanate14-3-3 protein etatarget
DB12695Phenethyl Isothiocyanate14-3-3 protein thetatarget
DB12695Phenethyl Isothiocyanate14-3-3 protein zeta/deltatarget
DB083982-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridineEstrogen receptor alphatarget
DB083982-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridineNuclear receptor coactivator 2target