DrugDrug NameDrug Description
DB00577ValaciclovirAn guanine nucleoside antiviral used to treat herpes exacerbations.
DB00616CandoxatrilCandoxatril is the orally-active prodrug of candoxatrilat (UK-73967), a potent neutral endopeptidase (NEP) inhibitor.
DB00623FluphenazineA phenothiazine used to treat patients requiring long-term neuroleptic therapy.
DB00799TazaroteneAn acetylenic retinoid used to treat fine wrinkles, mottled pigmentation of the skin, acne vulgaris, and plaque psoriasis.
DB01014BalsalazideAn aminosalicylate used to treat ulcerative colitis.
DB01320FosphenytoinAn antiepileptic agent used for the management of generalized convulsive status epilepticus and prevention and treatment of seizures occurring during neurosurgery.
DB01408BambuterolFor the prevention and reversal of bronchospasm in patients 12 years of age and older with asthma and reversible bronchospasm associated with bronchitis and emphysema.
DB01416CefpodoximeA third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including gonorrhea, community acquired pneumonia, and sinusitis.
DB04253TretazicarTretazicar is under investigation in clinical trial NCT00746590 (Study of Anti-tumour Effects and Safety of Prolarix™ in Hepatocellular Carcinoma).
DB06604IlepatrilInvestigated for use/treatment in hypertension.
DB09288PropacetamolPropacetamol is a paracetamol prodrug of intravenous administration used to control fever and pain of perioperative period in multimodal analgesia therapy.
DB11362SelexipagA non prostanoid IP prostacyclin receptor agonist used to treat pulmonary arterial hypertension.
DB14207FosinoprilatFosinoprilat is the active phosphinic acid metabolite of prodrug fosinopril, which is activated by esterases in vivo. It binds zinc with phosphinic acid group.
DB15566Prednisolone acetateA glucocorticoid used to treat a wide variety of endocrine, inflammatory, and immune conditions as well as for palliation of neoplastic conditions.
DrugDrug NameTargetType
DB00577ValaciclovirThymidine kinasetarget
DB00577ValaciclovirDNA polymerase catalytic subunittarget
DB00577ValaciclovirSolute carrier family 15 member 1transporter
DB00577ValaciclovirSolute carrier family 15 member 2transporter
DB00577ValaciclovirSolute carrier family 22 member 8transporter
DB00577ValaciclovirSolute carrier family 22 member 6transporter
DB00577ValaciclovirSodium- and chloride-dependent neutral and basic amino acid transporter B(0+)transporter
DB00577ValaciclovirIleal sodium/bile acid cotransportertransporter
DB00577ValaciclovirGuanylate kinaseenzyme
DB00577ValaciclovirThymidine kinaseenzyme
DB00616CandoxatrilNeprilysintarget
DB00616CandoxatrilAngiotensin-converting enzymetarget
DB00623FluphenazineDopamine D2 receptortarget
DB00623FluphenazineCalmodulintarget
DB00623FluphenazineDopamine D1 receptortarget
DB00623FluphenazineCytochrome P450 2D6enzyme
DB00623FluphenazineP-glycoprotein 1transporter
DB00623FluphenazineCytochrome P450 2E1enzyme
DB00623FluphenazineAndrogen receptortarget
DB00623Fluphenazine5-hydroxytryptamine receptor 2Atarget
DB00623Fluphenazine5-hydroxytryptamine receptor 2Ctarget
DB00799TazaroteneRetinoic acid receptor alphatarget
DB00799TazaroteneRetinoic acid receptor RXR-betatarget
DB00799TazaroteneRetinoic acid receptor gammatarget
DB00799TazaroteneRetinoic acid receptor betatarget
DB00799TazaroteneCytochrome P450 2C8enzyme
DB01014BalsalazideProstaglandin G/H synthase 1target
DB01014BalsalazideProstaglandin G/H synthase 2target
DB01014BalsalazideArachidonate 5-lipoxygenasetarget
DB01014BalsalazidePeroxisome proliferator-activated receptor gammatarget
DB01014BalsalazideNADPH azoreductaseenzyme
DB01320FosphenytoinSodium channel protein type 5 subunit alphatarget
DB01320FosphenytoinCytochrome P450 2C19enzyme
DB01320FosphenytoinCytochrome P450 2B6enzyme
DB01320FosphenytoinCytochrome P450 2C9enzyme
DB01320FosphenytoinCytochrome P450 3A4enzyme
DB01320FosphenytoinSerum albumincarrier
DB01320FosphenytoinCytochrome P450 1A2enzyme
DB01320FosphenytoinUDP-glucuronosyltransferase 1-6enzyme
DB01320FosphenytoinUDP-glucuronosyltransferase 1-9enzyme
DB01320FosphenytoinThyroxine-binding globulincarrier
DB01408BambuterolBeta-2 adrenergic receptortarget
DB01408BambuterolCholinesteraseenzyme
DB01416CefpodoximePeptidoglycan synthase FtsItarget
DB04253TretazicarOxygen-insensitive NAD(P)H nitroreductasetarget
DB04253TretazicarRibosyldihydronicotinamide dehydrogenase [quinone]target
DB09288PropacetamolCholinesteraseenzyme
DB09288PropacetamolProstaglandin G/H synthase 1target
DB09288PropacetamolProstaglandin G/H synthase 2target
DB09288PropacetamolTransient receptor potential cation channel subfamily V member 1target
DB09288PropacetamolCannabinoid receptor 1target
DB09288PropacetamolCytochrome P450 2E1enzyme
DB09288PropacetamolCytochrome P450 1A2enzyme
DB09288PropacetamolCytochrome P450 2D6enzyme
DB09288PropacetamolUDP-glucuronosyltransferase 1-1enzyme
DB09288PropacetamolUDP-glucuronosyltransferase 1-6enzyme
DB09288PropacetamolUDP-glucuronosyltransferase 1-9enzyme
DB09288PropacetamolUDP-glucuronosyltransferase 2B15enzyme
DB09288PropacetamolUDP-glucuronosyltransferase 1-10enzyme
DB09288PropacetamolSulfotransferase 1A1enzyme
DB09288PropacetamolSulfotransferase 1A3/1A4enzyme
DB09288PropacetamolEstrogen sulfotransferaseenzyme
DB09288PropacetamolBile salt sulfotransferaseenzyme
DB09288PropacetamolArylamine N-acetyltransferase 2enzyme
DB09288PropacetamolCytochrome P450 2C9enzyme
DB09288PropacetamolCytochrome P450 3A4enzyme
DB11362SelexipagProstacyclin receptortarget
DB11362SelexipagLiver carboxylesterase 1enzyme
DB11362SelexipagCytochrome P450 2C8enzyme
DB11362SelexipagCytochrome P450 3A4enzyme
DB11362SelexipagSolute carrier organic anion transporter family member 1B1transporter
DB11362SelexipagSolute carrier organic anion transporter family member 1B3transporter
DB11362SelexipagP-glycoprotein 1transporter
DB15566Prednisolone acetateCorticosteroid-binding globulincarrier
DB15566Prednisolone acetateCytochrome P450 3A4enzyme
DB15566Prednisolone acetateGlucocorticoid receptortarget
DB15566Prednisolone acetateSolute carrier organic anion transporter family member 1A2transporter
DB15566Prednisolone acetateP-glycoprotein 1transporter
DB15566Prednisolone acetateSerum albumincarrier