- Accession Number
Organic compounds which contain P-C-P bonds, where P stands for phosphonates or phosphonic acids. These compounds affect calcium metabolism. They inhibit ectopic calcification and slow down bone resorption and bone turnover. Technetium complexes of diphosphonates have been used successfully as bone scanning agents.
- ATC Classification
Drug Drug Description Risedronic acid A bisphosphonate used to treat osteoporosis and Paget's disease. Etidronic acid A bisphosphonate drug that prevents osteoclastic bone resorption; used for the prevention and treatment of osteoporosis. Clodronic acid A bisphosphonate used to treat osteoporosis in postmenopausal women, hypercalcemia of malignancy, and osteolysis. Pamidronic acid A bisphosphonate used to treat Paget's disease, to treat hypercalcemia of malignancy, and to treat osteolytic bone lesions. Zoledronic acid A bisphosphonate used to treat malignancy associated hypercalcemia, multiple myeloma, and bone metastasis from solid tumors. Ibandronate A bisphosphonate used to treat osteoporosis in postmenopausal women. Alendronic acid A bisphosphonate drug that prevents osteoclastic bone resorption and is used for the prevention and treatment of osteoporosis. Tiludronic acid A bisphosphonate used for the treatment of Paget's disease of bone. Incadronic acid Incadronate has been investigated in the treatment of myeloma,[A14426,A14431] leukemia, and other cancers. It has also been investigated in patients with hypercalcemia of malignancy.
- Drugs & Drug Targets