Monoterpenes

Name
Monoterpenes
Accession Number
DBCAT001046
Description

Compounds with a core of 10 carbons generally formed via the mevalonate pathway from the combination of 3,3-dimethylallyl pyrophosphate and isopentenyl pyrophosphate. They are cyclized and oxidized in a variety of ways. Due to the low molecular weight many of them exist in the form of essential oils (OILS, VOLATILE).

Drugs
DrugDrug Description
MecamylamineA nicotine antagonist used to treat moderate to severe essential hypertension and uncomplicated malignant hypertension.
FencamfaminFor the the treatment of depressive fatigue in convalescence and other debilitated states as well as in the treatment of depressive day-time fatigue, lack of concentration and lethargy.
CamphorA compound used topically to help relieve pain and also as a topical antiseptic. May also be used in vaporizers to help suppress coughing. This medication should not be swallowed.
ThymolAn essential oil found in various over-the-counter antibacterial and antifungal products.
ThiocamphorNot Available
NorcamphorNot Available
CamphaneNot Available
PermethrinAn insecticide used to prevent infestation with Sarcoptes scabiei (scabies).
CenisertibInvestigated for use/treatment in solid tumors, leukemia (myeloid), myelodysplastic syndrome, and cancer/tumors (unspecified).
DeramciclaneInvestigated for use/treatment in anxiety disorders.
BlinatumomabAn antineoplastic antibody used to treat Philadelphia chromosome-negative relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL).
EcamsuleA sunscreen agent found in sunscreens that absorbs UV rays.
Pyrethrum extractA chrysanthemum flower extract used to treat head, pubic, and body lice.
EnzacameneAn ingredient used in sunscreen to block UVB radiation.
BorneolNot Annotated
Terpin hydrateAn expectorant used to treat bronchitis, pneumonia, bronchiectasis, COPD, and infectious or inflammatory diseases of the upper respiratory tract.
DeltamethrinNot Annotated
XibornolNot Annotated
PhenothrinNot Annotated
CypermethrinNot Annotated
BioallethrinBioallethrin was used for lice and scabies infestation. Other pyrethroids are now used in place of bioallethrin.
TetramethrinNot Annotated
CyfluthrinNot Annotated
Bornyl acetateNot Annotated
BifenthrinBifenthrin is under investigation in clinical trial NCT01560247 (Percutaneous Recanalization in Ischemic Stroke Management in Europe Observational Registry).
EucalyptolA common ingredient in mouthwash and cosmetics derived naturally from the eucalyptus plant that is frequently used to to improve symptoms of airway mucus hypersecretion.
(4R)-limoneneLimonene is common in cosmetic products. As the main odor constituent of citrus (plant family Rutaceae), D-limonene is used in food manufacturing and some medicines, e.g. as a flavoring to...
LevomentholAn organic compound used to treat mild to moderate muscle and joint pain.
Drugs & Drug Targets
DrugTargetType
MecamylamineNeuronal acetylcholine receptor subunit alpha-2target
MecamylamineNeuronal acetylcholine receptor subunit alpha-7target
MecamylamineNeuronal acetylcholine receptor subunit alpha-4target
MecamylamineNeuronal acetylcholine receptor subunit beta-2target
FencamfaminSodium-dependent dopamine transportertarget
CamphorCamphor 5-monooxygenasetarget
CamphorTransient receptor potential cation channel subfamily V member 1target
CamphorTransient receptor potential cation channel subfamily V member 3target
CamphorTransient receptor potential cation channel subfamily A member 1target
CamphorTransient receptor potential cation channel subfamily M member 8target
ThiocamphorCamphor 5-monooxygenasetarget
NorcamphorCamphor 5-monooxygenasetarget
CamphaneCamphor 5-monooxygenasetarget
PermethrinCytochrome P450 2B6enzyme
PermethrinSodium channel protein type 1 subunit alphatarget
PermethrinEstrogen receptor alphatarget
PermethrinNuclear receptor subfamily 1 group I member 2target
CenisertibAurora kinase Atarget
Deramciclane5-hydroxytryptamine receptor 2Atarget
Deramciclane5-hydroxytryptamine receptor 2Ctarget
DeramciclaneCytochrome P450 2D6enzyme
BlinatumomabB-lymphocyte antigen CD19target
BlinatumomabT-cell surface glycoprotein CD3 delta chaintarget
Pyrethrum extractNuclear receptor subfamily 1 group I member 2target
EnzacameneProgesterone receptortarget
EnzacameneAndrogen receptortarget
EnzacameneEstrogen receptor betatarget
EnzacameneEstrogen receptor alphatarget
BioallethrinVoltage-gated sodium channel alpha subunittarget
BioallethrinSodium channel proteintarget
BioallethrinVoltage-dependent calcium channeltarget
BioallethrinVoltage-dependent T-type calcium channeltarget
BioallethrinVoltage-dependent P/Q-type calcium channeltarget
BioallethrinVoltage-dependent L-type calcium channeltarget
BioallethrinCytochrome P450 2C8enzyme
BioallethrinCytochrome P450 2C9enzyme
BioallethrinCytochrome P450 2C19enzyme
BioallethrinCytochrome P450 3A4enzyme
BioallethrinCytochrome P450 2A1enzyme
BioallethrinCytochrome P450 1A1enzyme
BioallethrinCytochrome P450 2C6enzyme
BioallethrinCytochrome P450 2C11enzyme
BioallethrinCytochrome P450 3A1enzyme
BioallethrinCytochrome P450 3A2enzyme
LevomentholTransient receptor potential cation channel subfamily A member 1target
LevomentholTransient receptor potential cation channel subfamily M member 8target
LevomentholTransient receptor potential cation channel subfamily V member 3target
LevomentholKappa-type opioid receptortarget
LevomentholVoltage-dependent L-type calcium channeltarget
LevomentholCytochrome P450 3A4enzyme