Monoterpenes

Compounds with a core of 10 carbons generally formed via the mevalonate pathway from the combination of 3,3-dimethylallyl pyrophosphate and isopentenyl pyrophosphate. They are cyclized and oxidized in a variety of ways. Due to the low molecular weight many of them exist in the form of essential oils (OILS, VOLATILE).
DrugDrug NameDrug Indication
DB00657MecamylamineFor the treatment of moderately severe to severe essential hypertension and in uncomplicated cases of malignant hypertension
DB01463FencamfaminFor the the treatment of depressive fatigue in convalescence and other debilitated states as well as in the treatment of depressive day-time fatigue, lack of concentration and lethargy.
DB01744CamphorNot Available
DB02513ThymolNot Available
DB02851ThiocamphorNot Available
DB03540NorcamphorNot Available
DB04501CamphaneNot Available
DB04930PermethrinFor the treatment of infestation with Sarcoptes scabiei (scabies).
DB06347CenisertibInvestigated for use/treatment in solid tumors, leukemia (myeloid), myelodysplastic syndrome, and cancer/tumors (unspecified).
DB06512DeramciclaneInvestigated for use/treatment in anxiety disorders.
DB09052BlinatumomabIndicated for the treatment of Philadelphia chromosome-negative relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL).
DB09534EcamsuleApplied topically to filter out UVA rays.
DB11087Pyrethrum extractNot Available
DB11219EnzacameneIndicated for use as an active sunscreen agent.
DB11288BorneolNot Available
DB13163Terpin hydrateTerpin hydrate is used in the treatment of acute and chronic bronchitis, pneumonia, bronchiectasis, chronic obstructive pulmonary disease, infectious and inflammatory diseases of the upper respiratory tract.
DB13600DeltamethrinNot Available
DB13714XibornolNot Available
DB13717PhenothrinNot Available
DB13721CypermethrinNot Available
DB13746BioallethrinBioallethrin was used for lice and scabies infestation. Other pyrethroids are now used in place of bioallethrin.
DB13752TetramethrinNot Available
DB13828CyfluthrinNot Available
DB14665Bornyl acetateNot Available
DB15056BifenthrinNot Available
DrugDrug NameTargetType
DB00657MecamylamineNeuronal acetylcholine receptor subunit alpha-2target
DB00657MecamylamineNeuronal acetylcholine receptor subunit alpha-7target
DB00657MecamylamineNeuronal acetylcholine receptor subunit alpha-4target
DB00657MecamylamineNeuronal acetylcholine receptor subunit beta-2target
DB01463FencamfaminSodium-dependent dopamine transportertarget
DB01744CamphorCamphor 5-monooxygenasetarget
DB01744CamphorTransient receptor potential cation channel subfamily V member 1target
DB01744CamphorTransient receptor potential cation channel subfamily V member 3target
DB01744CamphorTransient receptor potential cation channel subfamily A member 1target
DB01744CamphorTransient receptor potential cation channel subfamily M member 8target
DB02851ThiocamphorCamphor 5-monooxygenasetarget
DB03540NorcamphorCamphor 5-monooxygenasetarget
DB04501CamphaneCamphor 5-monooxygenasetarget
DB04930PermethrinCytochrome P450 2B6enzyme
DB04930PermethrinCytochrome P450 3A4enzyme
DB04930PermethrinSodium channel protein type 1 subunit alphatarget
DB04930PermethrinEstrogen receptor alphatarget
DB04930PermethrinNuclear receptor subfamily 1 group I member 2target
DB06347CenisertibAurora kinase Atarget
DB06512Deramciclane5-hydroxytryptamine receptor 2Atarget
DB06512Deramciclane5-hydroxytryptamine receptor 2Ctarget
DB06512DeramciclaneCytochrome P450 2D6enzyme
DB09052BlinatumomabB-lymphocyte antigen CD19target
DB09052BlinatumomabT-cell surface glycoprotein CD3 delta chaintarget
DB11087Pyrethrum extractNuclear receptor subfamily 1 group I member 2target
DB11219EnzacameneProgesterone receptortarget
DB11219EnzacameneAndrogen receptortarget
DB11219EnzacameneEstrogen receptor betatarget
DB11219EnzacameneEstrogen receptor alphatarget
DB13746BioallethrinVoltage gated sodium channeltarget
DB13746BioallethrinSodium channel proteintarget
DB13746BioallethrinVoltage-dependent N-type calcium channeltarget
DB13746BioallethrinVoltage-dependent T-type calcium channeltarget
DB13746BioallethrinVoltage-dependent P/Q-type calcium channeltarget
DB13746BioallethrinVoltage-dependent L-type calcium channeltarget
DB13746BioallethrinCytochrome P450 2C8enzyme
DB13746BioallethrinCytochrome P450 2C9enzyme
DB13746BioallethrinCytochrome P450 2C19enzyme
DB13746BioallethrinCytochrome P450 3A4enzyme
DB13746BioallethrinCytochrome P450 2A1enzyme
DB13746BioallethrinCytochrome P450 1A1enzyme
DB13746BioallethrinCytochrome P450 2C6enzyme
DB13746BioallethrinCytochrome P450 2C11enzyme
DB13746BioallethrinCytochrome P450 3A1enzyme
DB13746BioallethrinCytochrome P450 3A2enzyme