Cyclodecanes

Name
Cyclodecanes
Accession Number
DBCAT001310
Description

Compounds with a 10-carbon ring.

Drugs
DrugDrug Description
PaclitaxelA taxoid chemotherapeutic agent used as first-line and subsequent therapy for the treatment of advanced carcinoma of the ovary, and other various cancers including breast and lung cancer.
DocetaxelA taxoid antineoplastic agent used in the treatment of various cancers, such as locally advanced or metastatic breast cancer, metastatic prostate cancer, gastric adenocarcinoma, and head and neck cancer.
Paclitaxel docosahexaenoic acidInvestigated for use/treatment in breast cancer, colorectal cancer, gastric cancer, kidney cancer, lung cancer, pancreatic cancer, prostate cancer, and skin cancer.
AI-850Investigated for use/treatment in breast cancer and solid tumors.
Paclitaxel trevatideInvestigated for use/treatment in brain cancer.
CabazitaxelAn antineoplastic agent used for the treatment of hormone-refractory metastatic prostate cancer previously treated with a docetaxel-containing treatment regimen.
OrtataxelOrtataxel has been used in trials studying the treatment of Lymphoma, Lung Cancer, Glioblastoma, and Kidney Cancer.
TesetaxelTesetaxel has been used in trials studying the treatment of Cancer, Melanoma, Prostate Cancer, Gastric Carcinoma, and Advanced Melanoma, among others.
MilataxelMilataxel has been used in trials studying the treatment of Mesothelioma.
BMS-188797BMS-188797 has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.
BMS-184476BMS-184476 has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.
LarotaxelLarotaxel has been used in trials studying the treatment of Cancer, Metastases, Breast Cancer, Breast Neoplasms, and Pancreatic Neoplasms, among others.
Paclitaxel poliglumexNot Annotated
SimotaxelSimotaxel is under investigation in clinical trial NCT00088647 (Study Evaluating MST-997 in Advanced Malignant Solid Tumors).
Drugs & Drug Targets
DrugTargetType
PaclitaxelApoptosis regulator Bcl-2target
PaclitaxelTubulin beta-1 chaintarget
PaclitaxelCytochrome P450 2C8enzyme
PaclitaxelCytochrome P450 3A4enzyme
PaclitaxelCytochrome P450 3A5enzyme
PaclitaxelCytochrome P450 3A7enzyme
PaclitaxelBile salt export pumptransporter
PaclitaxelP-glycoprotein 1transporter
PaclitaxelMultidrug resistance-associated protein 1transporter
PaclitaxelMultidrug resistance-associated protein 7transporter
PaclitaxelCytochrome P450 19A1enzyme
PaclitaxelCytochrome P450 1B1enzyme
PaclitaxelSolute carrier organic anion transporter family member 1B3transporter
PaclitaxelNuclear receptor subfamily 1 group I member 2target
PaclitaxelMicrotubule-associated protein 4target
PaclitaxelMicrotubule-associated protein 2target
PaclitaxelMicrotubule-associated protein tautarget
PaclitaxelCanalicular multispecific organic anion transporter 1transporter
DocetaxelApoptosis regulator Bcl-2target
DocetaxelTubulin beta-1 chaintarget
DocetaxelCytochrome P450 3A4enzyme
DocetaxelCytochrome P450 3A5enzyme
DocetaxelCytochrome P450 3A7enzyme
DocetaxelP-glycoprotein 1transporter
DocetaxelMultidrug resistance-associated protein 7transporter
DocetaxelCytochrome P450 1B1enzyme
DocetaxelMicrotubule-associated protein 2target
DocetaxelMicrotubule-associated protein 4target
DocetaxelMicrotubule-associated protein tautarget
DocetaxelSolute carrier organic anion transporter family member 1B3transporter
DocetaxelSolute carrier family 22 member 7transporter
DocetaxelATP-binding cassette sub-family G member 2transporter
DocetaxelCanalicular multispecific organic anion transporter 1transporter
DocetaxelMultidrug resistance-associated protein 1transporter
DocetaxelNuclear receptor subfamily 1 group I member 2target
Paclitaxel docosahexaenoic acidApoptosis regulator Bcl-2target
CabazitaxelCytochrome P450 3A4enzyme
CabazitaxelCytochrome P450 3A5enzyme
CabazitaxelCytochrome P450 2C8enzyme
CabazitaxelP-glycoprotein 1transporter
CabazitaxelATP-binding cassette sub-family G member 2transporter
CabazitaxelTubulin alpha-4A chaintarget
CabazitaxelTubulin beta-1 chaintarget
CabazitaxelSolute carrier organic anion transporter family member 1B1transporter
CabazitaxelSolute carrier organic anion transporter family member 1B3transporter
MilataxelTubulin beta-1 chaintarget
MilataxelTubulin beta chaintarget