Derivatives of phosphatidic acid in which the hydrophobic regions are composed of two fatty acids and a polar alcohol is joined to the C-3 position of glycerol through a phosphodiester bond. They are named according to their polar head groups, such as phosphatidylcholine and phosphatidylethanolamine.
DrugDrug NameDrug Description
DB02261Platelet Activating FactorNot Available
DB04327PhosphatidylethanolamineNot Available
DB04660Choline alfoscerateA component of phosphatidylcholines (lecithins), in which the two hydroxy groups of glycerol are esterified with fatty acids. (From Stedman, 26th ed) It counteracts the effects of urea on enzymes...
DB04897LucinactantIntended for the prevention of respiratory distress syndrome (RDS) in premature infants at high risk for RDS.
DB05456ETC-588Investigated for use/treatment in atherosclerosis, coronary artery disease, and vascular diseases.
DB09114Colfosceril palmitateA pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants.
DB11283DL-dimyristoylphosphatidylcholineDL-dimyristoylphosphatidylcholine is not an active pharmaceutical agent and has no indication.
DB11284DL-dimyristoylphosphatidylglycerolDL-dimyristoylphosphatidylglycerol is not an considered an active pharmacological ingredient in pharmaceutical preparations and so has no official indications.
DB13615MifamurtideA muramyl dipeptide derivative used to treat high grade, resectable, non-metastatic osteosarcoma after surgical resection.
DB140991,2-DistearoyllecithinNot Annotated
DB15259VB-201VB-201 is under investigation in clinical trial NCT01001468 (Study to Assess VB-201 in Patients With Psoriasis).
DB00144Phosphatidyl serineA nutrient used in some supplement products.